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Keywords: intracellular antibody
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Articles
Targeting small GTPases and their downstream pathways with intracellular macromolecule binders to define alternative therapeutic strategies in cancer
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2021–2035.
Published: 08 October 2021
...) at their surface. Therefore, alternative therapeutic strategies have been developed to target these proteins. In this review, we discuss the use of intracellular antibodies and derivatives — reagents that bind their antigen inside the cells — for the discovery of novel inhibitory mechanisms, targetable features...
