... Society 2024 cancer cell death ferroptosis ischaemia-reperfusion injury lipid peroxidation oxidative stress Approximately 2.4 billion years ago, ‘The Great Oxygenation event’ changed the earth's atmospheric landscape. The significant increase in atmospheric oxygen levels introduced new...

... production and for pathologies resulting from substantial succinate oxidation in vivo . bioenergetics ischaemia-reperfusion injury membrane potential mitochondria reactive oxygen species thermodynamics The operation of a biological system is like the operation of a factory: each machine...

...-coupled receptors ischaemia–reperfusion injury lipids The G protein-coupled receptor (GPCR) family include a large number of structurally related seven transmembrane-spanning receptors that bind unique or shared ligands that can act as full-, partial-, inverse-agonists, or antagonists. GPCR...

...Fang Cao; Sevasti Zervou; Craig A. Lygate Restoring blood flow following an acute myocardial infarction saves lives, but results in tissue damage due to ischaemia–reperfusion injury (I/R). Ameliorating this damage is a major research goal to improve recovery and reduce subsequent morbidity due...

... 2015 © 2016 Authors; published by Portland Press Limited 2016 heart failure Inorganic polyphosphate ischaemia-reperfusion injury mitochondria mitochondrial permeability transition pore poly-β-hydroxybutyrate Inorganic polyphosphate (polyP) is one of the several molecules...