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Keywords: isoform-selective inhibitor
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Biochem Soc Trans (2004) 32 (2): 393–396.
Published: 01 April 2004
...-knockout mouse models. Prototype inhibitors show evidence of anticancer activity in vitro and in vivo animal models. The recent development of isoform-selective inhibitors shows considerable promise for cancer treatment. 1 e-mail: paul.workman@icr.ac.uk PI-3 Kinase in Signalling and Disease...