.... 1 To whom correspondence should be addressed (email [email protected] ). 13 4 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 bipolar disorder glycogen synthase kinase 3β (GSK3β) inositol monophosphatase (IMPase) knockout mouse lithium sodium– myo...

... isoforms. I discuss gene disruption studies in mice that reveal redundant or limited roles for individual isoforms, along with evidence for potential autoimmunity when class IA PI3K signalling is reduced. autoimmunity knockout mouse phosphoinositide 3-kinase (PI3K) regulatory T-cell (Treg) T-cell...

... of Lipids, a meeting held at Keble College, Oxford, 7–11 September 2003 7 September 2003 © 2004 Biochemical Society 2004 apolipoprotein E (apoE) atherosclerosis inflammation knockout mouse serum chemokine Abbreviations used: apoE, apolipoprotein E; oxLDL, oxidized low...

... homeostasis. © 2002 Biochemical Society 2002 1 e-mail [email protected] 19 10 2001 IRS, insulin receptor substrate IGF, insulin-like growth factor βIRKO, β-cell insulin receptor knockout βIGFRKO, β-cell IGF-1 receptor knockout β-cell knockout mouse...

... of the insulin receptor causes a similar phenotype, these findings implicate IRS signalling pathways in the neuroendocrine regulation of reproduction and energy homeostasis. 1 e-mail [email protected] 7 3 2001 © 2001 Biochemical Society 2001 insulin knockout mouse metabolism...