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Keywords: lentiviral vector
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Articles
Attacking HIV-1 RNA versus DNA by sequence-specific approaches: RNAi versus CRISPR-Cas
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (5): 1355–1365.
Published: 19 October 2016
... palindromic repeats (CRISPR-Cas) mechanisms will be described, which can be delivered by lentiviral vectors. These mechanisms attack different forms of the viral genome, the RNA and DNA, respectively, but both mechanisms act in a strictly sequence-specific manner. Early RNAi experiments demonstrated profound...
