... conformational change has been observed between apparent carrier and active forms of DNA ligase I bound to PCNA. In the absence of its DNA substrate, DNA ligase I adopts an elongated configuration radiating out from the PCNA ring, which presumably allows other proteins to bind the ring and engage DNA [ 53...

...P.A. Sunderland; C.E. West; W.M. Waterworth; C.M. Bray DNA ligase 1 ( AtLIG1 ) is the only essential DNA ligase activity in Arabidopsis and is implicated in the important processes of DNA replication, repair and recombination and in transgene insertion during Agrobacterium -mediated plant...