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Keywords: lineage tracing
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Articles
Mechanisms of vascular smooth muscle cell investment and phenotypic diversification in vascular diseases
Open Access
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2101–2111.
Published: 08 September 2021
... remodelling characteristic of atherosclerosis, restenosis, aneurysm and pulmonary arterial hypertension. Clonal lineage tracing revealed that the VSMC-contribution to disease results from the hyperproliferation of few pre-existing medial cells and suggested that VSMC-derived cells from the same clone can...
