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Keywords: lipid metabolism
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Biochem Soc Trans (2023) 51 (1): 223–232.
Published: 06 February 2023
... chronic kidney disease gluconeogenesis inflammation lipid metabolism renal physiology Chronic kidney disease (CKD) is clinically defined as reduced kidney function or a structural abnormality that lasts longer than 3 months. With the loss of functional nephrons and reduction in glomerular...
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Biochem Soc Trans (2022) 50 (3): 1191–1204.
Published: 23 May 2022
.... In view of the emerging role of circadian regulation in maintaining lipid homeostasis, in this review, we summarize the current knowledge on lipid metabolic pathways controlled by the mammalian circadian system. Furthermore, we review the emerging connection between the development of human metabolic...
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Biochem Soc Trans (2019) 47 (5): 1291–1305.
Published: 28 October 2019
... 2019 27 9 2019 1 10 2019 © 2019 The Author(s) 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . lipid metabolism lipid-binding domains...
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Biochem Soc Trans (2019) 47 (5): 1259–1268.
Published: 18 October 2019
... and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . ATP-binding cassette transporters cardiovascular disease cholesterol transport lipid metabolism sitosterolemia structural biology Cardiovascular diseases are the leading cause of death globally (∼50% deaths...
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Biochem Soc Trans (2015) 43 (5): 1079–1084.
Published: 09 October 2015
... TRIB1 locus as being significantly associated with multiple plasma lipid traits and cardiovascular disease (CVD) in humans. The involvement of TRIB1 in hepatic lipid metabolism has been validated through viral-mediated hepatic overexpression of the gene in mice; increasing levels of TRIB1 decreased...
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Biochem Soc Trans (2015) 43 (2): 235–239.
Published: 07 April 2015
... apparatus or plasma membrane [ 2 ]. This subcellular distribution in turn dictates Ras protein access to a number of effector molecules that regulate diverse cellular responses [ 1 ]. intercellular signalling lipid metabolism membrane bound O-acyltransferases protein fatty acylation Wnt Hedgehog...
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Biochem Soc Trans (2015) 43 (1): 108–110.
Published: 26 January 2015
... encounter structure (ERMES) lipid metabolism mitochondria mitophagy small GTPase The communication between organelles of the secretory pathway is an essential part of the life of any eukaryote. Transport containers are formed at one organelle and move in a vectorial manner to the next organelle...
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Biochem Soc Trans (2011) 39 (4): 910–916.
Published: 20 July 2011
...-onset disorder. Alzheimer's disease amyloid β-peptide complement system disease modelling genome-wide association study (GWAS) lipid metabolism The recent advances in AD (Alzheimer's disease) genetics brought several new players to the pathways involved in this already complex...
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Biochem Soc Trans (2006) 34 (6): 1110–1113.
Published: 25 October 2006
...) separated by a 4-nt spacer, termed a DR4 (direct repeat-4) [ 5 ]. These LXR-response elements appear throughout the genome and are responsible for the physiological responses mediated by the transcriptional activation of LXR by oxysterols. adrenal gland cholesterol corticosterone lipid...
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Biochem Soc Trans (2006) 34 (3): 377–380.
Published: 22 May 2006
... homology to Sec14p and together they form the Sec14p family of lipid-transfer proteins. It is a diverse group of proteins with distinct subcellular localizations and varied physiological functions related to lipid metabolism and membrane trafficking. 1 To whom correspondence should be addressed...
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Biochem Soc Trans (2005) 33 (5): 1053–1058.
Published: 26 October 2005
... factor linking the clinical manifestations of the metabolic syndrome. 1 To whom correspondence should be addressed (email [email protected] ). 20 6 2005 © 2005 The Biochemical Society 2005 energy balance homoeostasis insulin resistance lipid metabolism mouse model...
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Biochem Soc Trans (2005) 33 (5): 1178–1181.
Published: 26 October 2005
... correspondence should be addressed (email [email protected] ). 31 5 2005 Most enzymes involved in the lipid metabolism of yeast have been identified and the corresponding genes have been cloned. Therefore information on the regulation of the individual pathways is abundant. A number of recent...
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Biochem Soc Trans (2004) 32 (1): 107–109.
Published: 01 February 2004
... on the Bioscience of Lipids, a meeting held at Keble College, Oxford, 7–11 September 2003 7 September 2003 © 2004 Biochemical Society 2004 hepatocyte nuclear factor-4 (HNF-4) lipid metabolism lipogenesis sterol regulatory element-binding protein 1c (SREBP-1c) Abbreviations used...
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Biochem Soc Trans (2000) 28 (6): 834–836.
Published: 01 December 2000
... of 14-3-3 proteins. Several enzymes can be modified after 14-3-3 binding, among them nitrate re- ductase and sucrose phosphate synthase, i.e. key Key words: lipid metabolism, protein interactions. Abbreviations used: LOX, lipoxygenase: PPZA, protein phosphatase 2A; HMM, high-molecular-mass; FC...