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Keywords: lipids
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Biochem Soc Trans (2024) 52 (2): 639–650.
Published: 20 March 2024
... 2i/LIF medium has provided solutions to some of these challenges, prolonged culturing of these cells, especially female ESCs, raises concerns related to genome integrity. This review discusses the pivotal role of lipids in genome stability and pluripotency of stem cells. Notably, the introduction...
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Biochem Soc Trans (2022) 50 (1): 1–11.
Published: 28 February 2022
... were still largely unknown. The molecular biology revolution was only beginning, and researchers looked forward to the application of cDNA cloning approaches which would help identify the key genes and their products involved in PL remodelling. lipids membranes phospholipids William...
Biochem Soc Trans (2022) 50 (1): 555–567.
Published: 25 February 2022
...Ryan Brady; Nicola J. Harris; Grant A. Pellowe; Samuel Gulaidi Breen; Paula J. Booth Membrane proteins need to fold with precision in order to function correctly, with misfolding potentially leading to disease. The proteins reside within a hydrophobic lipid membrane and must insert...
Biochem Soc Trans (2019) 47 (3): 897–908.
Published: 30 May 2019
... with signaling at the plasma membrane, PI(3,4)P 2 is gaining increasing traction as a signaling lipid and has been implicated in controlling Akt activity throughout the endomembrane system. This has clear implications for the phosphorylation of both freely diffusible substrates and those localized to discrete...
Biochem Soc Trans (2019) 47 (2): 743–754.
Published: 22 March 2019
...Monica Napolitano The G protein-coupled receptors (GPCRs) constitute a large superfamily of seven transmembrane-spanning receptors that are activated by several classes of ligands, including bioactive lipids. GPCRs are attractive therapeutic targets for the treatment of human diseases...
Biochem Soc Trans (2018) 46 (2): 379–389.
Published: 14 March 2018
...Tamako Nishimura; Nobuhiro Morone; Shiro Suetsugu Lipid membranes are structural components of cell surfaces and intracellular organelles. Alterations in lipid membrane shape are accompanied by numerous cellular functions, including endocytosis, intracellular transport, and cell migration. Proteins...
Biochem Soc Trans (2017) 45 (2): 297–302.
Published: 13 April 2017
...John L. Harwood Lipids are key molecules for membranes, energy storage and signalling. I have been privileged to have worked in such a diverse field and in organisms from microbes to humans. Here I will describe some of those contrasting areas which range from environmental impacts to food...
Biochem Soc Trans (2015) 43 (5): 1049–1050.
Published: 09 October 2015
...Endre Kiss-Toth; Guillermo Velasco; Warren S. Pear 1 To whom correspondence should be addressed (email [email protected] ) . 2 6 2015 © 2015 Authors; published by Portland Press Limited 2015 cancer lipids metabolism signalling tribbles ubiquitin...
Biochem Soc Trans (2004) 32 (6): 1051–1056.
Published: 26 October 2004
...J. Shepherd The evidence linking cholesterol levels in the blood to vascular risk is now incontrovertible and the introduction of HMG CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitor (or statin) therapy into clinical practice has now revolutionized the management of lipid disorders...
Biochem Soc Trans (2000) 28 (6): 902–905.
Published: 01 December 2000
...A. Smaoui; A. Chérif Cotton plants ( Gossypium hirsutum L. cv. S4) were grown and irrigated with increasing salt concentrations: 0, 50, 100 and 150 mM NaCl. Lipids from developing seeds, at stages of 3, 4, 5 and 6 weeks after anthesis, were analysed. High salt dose (150 mM NaCl) affected...