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Keywords: lipotoxicity
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Articles
Biochem Soc Trans (2008) 36 (5): 909–915.
Published: 19 September 2008
... progress in the field of ER stress in pancreatic β-cells. Recent advances in the understanding of lipotoxic ER stress and β-cell recovery from ER stress are discussed. 11 6 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 apoptosis diabetes endoplasmic reticulum...
Articles
Biochem Soc Trans (2008) 36 (5): 916–919.
Published: 19 September 2008
... (email t.biden@garvan.org.au ). 21 4 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 glucose-stimulated insulin secretion insulin secretion lipotoxicity pancreatic β-cell protein kinase C (PKC) Type 2 diabetes Multiple PKC isoforms are expressed...
Articles
Biochem Soc Trans (2008) 36 (5): 930–934.
Published: 19 September 2008
... of ROS and are also the primary target of oxidative attacks. The present review presents the current knowledge of lipotoxicity related to oxidative stress in the context of mitochondrial function in the β-cell. 1 To whom correspondence should be addressed (email Pierre.Maechler@medecine.unige.ch...
Articles
Biochem Soc Trans (2008) 36 (3): 348–352.
Published: 21 May 2008
... 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 apoptosis diabetes mellitus lipoprotein lipotoxicity non-esterified fatty acid pancreatic β-cell In parallel with the increase in life expectancy of the last two centuries, lifestyles have changed...
Articles
Biochem Soc Trans (2006) 34 (5): 819–823.
Published: 25 October 2006
... in mitochondrial function in adipose cells seems to result in an inappropriate scavenging of fatty acids by β-oxidation. As a consequence, a systemic overload with fatty acids occurs, leading to an enhanced decline in β-cell function due to lipotoxicity. 1 To whom correspondence should be addressed...