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Keywords: liquid–liquid phase separation
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Biochem Soc Trans (2022) 50 (1): 119–134.
Published: 23 December 2021
...-liquid phase separation state caused by these repeat RNAs and repeat polypeptides, as well as potential therapeutic approaches against repeat expansion diseases. Correspondence: Yoshitaka Nagai ( yoshi.nagai@med.kindai.ac.jp ) 24 9 2021 30 11 2021 6 12 2021 © 2022 The Author...
Biochem Soc Trans (2020) 48 (6): 2591–2602.
Published: 10 December 2020
...Pinaki Swain; Stephanie C. Weber Biomolecular condensates comprise a diverse and ubiquitous class of membraneless organelles. Condensate assembly is often described by liquidliquid phase separation. While this process explains many key features, it cannot account for the compositional...
Biochem Soc Trans (2016) 44 (5): 1411–1416.
Published: 19 October 2016
... different conditions, their biological functions and physical properties are poorly understood. Recent intriguing data suggest that liquidliquid phase separation (LLPS) represents an important mechanism seeding the formation and defining the function of RNPBs. In this review, we discuss how LLPS...