...Yun Ma; Siqi He; Tianhe Gu; Yixuan Liu; Shuya He; Zhisheng Jiang Long non-coding RNAs (lncRNAs) are a class of non-coding RNA with a length greater than 200 nt. It has a mRNA-like structure, formed by splicing after transcription, and contains a polyA tail and a promoter, of whom promoter plays...

...Ana Cláudia Raposo; Miguel Casanova; Anne-Valerie Gendrel; Simão Teixeira da Rocha X-inactive-specific transcript ( Xist ) is a long non-coding RNA (lncRNA) essential for X-chromosome inactivation (XCI) in female placental mammals. Thirty years after its discovery, it is still puzzling how...

... activation, alternative splicing, and DNA repair [ 12 , 13 ]. These RNA-regulated processes can be mis-regulated in disease, with examples of RNA-mediated heterochromatin formation contributing to many cancers [ 14 ]. chromatin lncRNA piRNA RNA matchmaking The term ‘RNA matchmaking...

... in order to establish totipotency in blastomeres of an early embryo. This remodeling involves replacement of maternal RNAs with zygotic RNAs through maternal RNA degradation and zygotic genome activation. This review is focused on expression and function of long noncoding RNAs (lncRNAs) and small RNAs...

...Loretta Magagula; Maria Gagliardi; Jerolen Naidoo; Musa Mhlanga Termed ‘master gene regulators’ long ncRNAs (lncRNAs) have emerged as the true vanguard of the ‘noncoding revolution’. Functioning at a molecular level, in most if not all cellular processes, lncRNAs exert their effects systemically...