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Keywords: mRNA localization
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Biochem Soc Trans (2020) 48 (6): 2565–2578.
Published: 27 November 2020
... in their function: modulating their composition, size, density, and the network-like architecture in relation to the metabolic demands of the cell. Here, we review the recent research on the post-transcriptional regulation of mitochondrial composition focusing on mRNA localization, mRNA translation, protein import...
Biochem Soc Trans (2014) 42 (4): 1256–1260.
Published: 11 August 2014
... be associated with translational repression or activation. Furthermore, mRNA P-bodies (processing bodies) harbour much of the mRNA decay machinery and stress granules are thought to play a role in mRNA storage. In the present review, we explore the process of mRNA localization in the yeast Saccharomyces...
Biochem Soc Trans (2011) 39 (5): 1161–1165.
Published: 21 September 2011
... motors during the localization process. Important outstanding questions will also be highlighted. 1 email sbullock@mrc-lmb.cam.ac.uk 22 3 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 cytoskeletal motor motility mRNA localization mRNA–protein...
Biochem Soc Trans (2009) 37 (5): 1066–1071.
Published: 21 September 2009
... partially, to a requirement for the protein in microtubule-dependent accumulation of oocyte-specific mRNAs [ 8 ]. Although BicD -null mutants fail to differentiate an oocyte, experiments in which BicD function is perturbed only partially have shown that the protein also plays a role in mRNA localization...
Biochem Soc Trans (2008) 36 (3): 525–527.
Published: 21 May 2008
..., such as the Drosophila embryo, where the spatial and temporal localization of bicoid and gurken mRNAs, among others, is required to establish morphogen gradients. More recent studies have suggested that mRNA localization also occurs with transcripts coding for membrane-based or secreted proteins, and that localization...
Biochem Soc Trans (2004) 32 (5): 705–706.
Published: 26 October 2004
...I. Mickleburgh; B. Burtle; D. Nury; H. Chabanon; Z. Chrzanowska-Lightowlers; J.E. Hesketh mRNA localization provides a mechanism for localized protein synthesis. mRNAs encoding certain proteins, including c-MYC, c-FOS, MT-1 (Metallothionein-1) and vimentin, are localized around the nuclei...