... chromatography (GC) liquid chromatography (LC) mass spectrometry (MS) matrix assisted laser desorption ionization (MALDI) Glucocorticoid hormones regulate diverse physiological functions, including immune, metabolic and stress responses, through their actions on nuclear hormone receptors (mainly...

..., indicating the potential for multiple pathways simultaneously driving tumour progression in a single model. acquired resistance mass spectrometry (MS) phosphoprotein signalling network therapeutic resistance Signalling and Acquired Resistance to Targeted Cancer Therapeutics: A Biochemical...

.... Altogether, this approach quadruples the number of high confidence palmitoylated proteins annotated in mouse T-cells by reproducibly and accurately quantifying fractional changes in protein enrichment [ 26 ] ( Figure 1 ). mass spectrometry (MS) palmitoylation post-translational modification...

... email [email protected] 4 4 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 advanced glycation end-product (AGE) advanced lipoxidation end-product (ALE) glycated peptide mass spectrometry (MS) protein sequencing Components...

... spectrometry (MS) Owing to the chemical and biological complexity of eicosanoids, measurements of their concentrations must be carefully validated. Although there are several approaches for determining these mediators, there are pitfalls that need to be avoided. The assay should be sensitive, specific...

... 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 arachidonic acid F 2 -isoprostane lipid peroxidation mass spectrometry (MS) oxidative stress Figure 2 Proposed pathways for biosynthesis and metabolism of prostaglandins X, Y and Z=O, OH or H. ( 1...

... oxidation and nitrosation are also implicated in some of these diseases, as well as environmental chemical- and drug-induced toxicity [2,3]. Glycation adducts are Key words: fructosamine, glycation, methionine sulphoxide, mass spectrometry (MS), nitrotyrosine, oxidative stress. Abbreviations used: AGE...

... ). Intermolecular Associations in 2D and 3D, a Biochemical Society Focused Meeting held at University of Nottingham, 19–20 June 2003 20 June 2003 © 2003 Biochemical Society 2003 electrospray ionization (ESI) Fourier-transform ion cyclotron resonance (FTICR) mass spectrometry (MS) non...