... metabolic reprogramming oxidative stress In 1836, Samuel Baup discovered an unknown product following the thermal decomposition of citric acid [ 1 ]. Four years later, Gustav Crasso synthesised the same compound by decarboxylation of cis -aconitate naming it itaconate — an anagram of aconitate [ 2...

... that cells undergo in response to iron deficit and the regulatory mechanisms that allow these adaptive responses. In the present article, we summarize recent work on genome-wide metabolic reprogramming in response to iron deficiency, mediated by specific mRNA degradation mechanisms that allow S. cerevisiae...