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Keywords: metabolomics
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Articles
Biochem Soc Trans (2021) 49 (5): 1905–1926.
Published: 10 August 2021
... understanding these organisms, and a substantial proportion of genes remain functionally unknown. Methodological advances, principally mass spectrometry (MS), are paving the way for parallel analysis of the proteome, metabolome and lipidome. Each provides a global, complementary assay, in addition to genomics...
Articles
Biochem Soc Trans (2019) 47 (1): 305–315.
Published: 30 January 2019
... new approaches in advanced microscopy, transcriptomics and metabolomics using zebrafish as a model system have yielded fundamental insights into the mechanistic underpinnings of disease. Correspondence: Andrew G. Cox ( Andrew.cox@petermac.org ) 25 10 2018 18 12 2018 2 1 2019...
Articles
Biochem Soc Trans (2016) 44 (2): 638–644.
Published: 11 April 2016
... 2016 insulin resistance liquid chromatography mass spectrometry metabolomics non-alcoholic fatty liver disease obesity type 2 diabetes Figure 1 Structure elucidation by fragmentation of a TAG during MS Structure elucidation of a given lipid by high resolution MS occurs in two...
Articles
Biochem Soc Trans (2014) 42 (5): 1447–1452.
Published: 18 September 2014
...-invasively the initial symptoms to stop, revert or even prevent disease development. In this context, merging metabolomics with other techniques and the interpretation of the huge information obtained resembles the ‘Rosetta stone’ to decipher the pathological metabolic fluxes that must be targeted to find...
Articles
Biochem Soc Trans (2013) 41 (2): 670–673.
Published: 21 March 2013
...Lorraine Brennan Metabolomics is the study of metabolites present in biological samples such as biofluids, tissue/cellular extracts and culture media. Combining metabolomic data with multivariate data analysis tools allows us to study alterations in metabolic pathways following different...
Articles
Biochem Soc Trans (2010) 38 (5): 1302–1306.
Published: 24 September 2010
...Marta Cascante; Adrian Benito; Miriam Zanuy; Pedro Vizán; Silvia Marín; Pedro de Atauri Metabolite concentrations and fluxes are the system variables that characterize metabolism. The systematic study of metabolite profiles is known as metabolomics; however, knowledge of the complete set...
Articles
Biochem Soc Trans (2005) 33 (6): 1427–1429.
Published: 26 October 2005
...P. Mendes; D. Camacho; A. de la Fuente The advent of large data sets, such as those produced in metabolomics, presents a considerable challenge in terms of their interpretation. Several mathematical and statistical methods have been proposed to analyse these data, and new ones continue to appear...
Articles
Biochem Soc Trans (2005) 33 (3): 520–524.
Published: 01 June 2005
... supposed, and we are now well placed to decode it. 1 email dbk@manchester.ac.uk 14 1 2005 © 2005 The Biochemical Society 2005 computational technology genetic programming machine learning metabolomics signal processing elements systems biology ‘Progress in science...
Articles
Biochem Soc Trans (2003) 31 (6): 1476–1478.
Published: 01 December 2003
... correlations into metabolomic networks and their relationships with the underlying biochemical pathways. 1 To whom correspondence should be addressed (e-mail steuer@agnld.uni-potsdam.de ). Unravelling Nature's Networks a Biochemical Society Focused Meeting held at University of Sheffield, 21 July...