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Keywords: methyl pyruvate
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Articles
Starvation in the midst of plenty: making sense of ceramide-induced autophagy by analysing nutrient transporter expression
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (1): 253–258.
Published: 20 January 2009
... a bioenergetic crisis by so severely limiting cellular access to extracellular nutrients that autophagy is insufficient to meet the metabolic demands of the cell. In keeping with this bioenergetic explanation for ceramide toxicity, methyl pyruvate, a membrane-permeable nutrient, protects cells from ceramide...