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Keywords: methyl pyruvate
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Biochem Soc Trans (2009) 37 (1): 253–258.
Published: 20 January 2009
... a bioenergetic crisis by so severely limiting cellular access to extracellular nutrients that autophagy is insufficient to meet the metabolic demands of the cell. In keeping with this bioenergetic explanation for ceramide toxicity, methyl pyruvate, a membrane-permeable nutrient, protects cells from ceramide...