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Keywords: microscopy
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Articles
Biochem Soc Trans (2021) 49 (5): 2123–2131.
Published: 08 September 2021
... controls the expression of many target genes that affect a diverse array of downstream responses important for alleviating stresses and regulating cell fates [ 20–22 ]. Long-term time-lapse microscopy, imaging cells on the timescale of days, revealed that the dynamics of the nuclear concentration of p53...
Articles
Biochem Soc Trans (2018) 46 (3): 729–740.
Published: 05 June 2018
...Lucien E. Weiss; Tal Naor; Yoav Shechtman The structural organization and dynamics of DNA are known to be of paramount importance in countless cellular processes, but capturing these events poses a unique challenge. Fluorescence microscopy is well suited for these live-cell investigations...
Articles
Biochem Soc Trans (2017) 45 (5): 1077–1085.
Published: 25 August 2017
.... Understanding how PRRs signal is of critical importance due to their potential as therapeutic targets to ameliorate symptoms of inflammatory diseases. The recent advances in microscopy, such as the discovery of fluorescent proteins and the breaking of the diffraction limit of light, offer a unique opportunity...
Articles
Biochem Soc Trans (2009) 37 (4): 914–917.
Published: 22 July 2009
... electrophoresis, these strands are pulled out into the agarose, forming a tail which, when stained with a fluorescent dye, can be analysed by fluorescence microscopy. The intensity of this tail reflects the amount of DNA damage sustained. Despite being such an established and widely used assay, there are still...
Articles
Biochem Soc Trans (2008) 36 (4): 749–753.
Published: 22 July 2008
... bacteria as ‘bags of DNA and proteins’, relatively little has been learnt about how they organize their life processes within cells. The mistaken perception of bacteria cells as unstructured systems arose partly because of the difficulty of performing studies by light microscopy due to their small size...
Articles
Biochem Soc Trans (2003) 31 (5): 1020–1027.
Published: 01 October 2003
...D.S. Lidke; P. Nagy; B.G. Barisas; R. Heintzmann; J.N. Post; K.A. Lidke; A.H.A. Clayton; D.J. Arndt-Jovin; T.M. Jovin We report the implementation and exploitation of fluorescence polarization measurements, in the form of anisotropy fluorescence lifetime imaging microscopy (rFLIM) and energy...