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1-29 of 29
Keywords: mitogen-activated protein kinase (MAPK)
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (5): 1069–1074.
Published: 09 October 2015
... and in disease development. 1 To whom correspondence should be addressed (email [email protected] ) . 29 4 2015 © 2015 Authors; published by Portland Press Limited 2015 chronic inflammation disease mitogen-activated protein kinase (MAPK) tribbles The TRIB...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (5): 1104–1107.
Published: 09 October 2015
... Press Limited 2015 acute myeloid leukaemia (AML) CCAAT/enhancer binding protein (C/EBP) haematopoiesis mitogen-activated protein kinase (MAPK) tribbles homolog 1 (Trib1) Pseudokinase proteins modulate multiple signalling pathways by interacting as kinase decoys or modulating proteasome...
Articles
Gopika N. Nithianandarajah-Jones, Bettina Wilm, Christopher E.P. Goldring, Jürgen Müller, Michael J. Cross
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (6): 1584–1589.
Published: 17 November 2014
...Gopika N. Nithianandarajah-Jones; Bettina Wilm; Christopher E.P. Goldring; Jürgen Müller; Michael J. Cross Extracellular-signal-regulated kinase 5 (ERK5), also termed big MAPK1 (BMK1), is the most recently discovered member of the mitogen-activated protein kinase (MAPK) family. It is expressed...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (1): 11–24.
Published: 23 January 2014
... κB kinase (IKK) innate immunity mitogen-activated protein kinase (MAPK) phosphoinositide 3-kinase (PI3K) salt-inducible kinase (SIK) Toll-like receptor (TLR) The innate immune system is our first line of defence against invading pathogens. Cells such as macrophages and dendritic cells...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (4): 987–994.
Published: 18 July 2013
... Journal compilation © 2013 Biochemical Society 2013 Ca 2+ /calmodulin-activated serine kinase (CASK) human epidermal growth factor receptor 3 (Her3) kinase suppressor of Ras (KSR) mitogen-activated protein kinase (MAPK) extracellular-signal-regulated kinase pseudokinase Raf In humans...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 90–93.
Published: 19 January 2012
... of the Twist transcription factor family, which also show a significant hypertrophy phenotype in the first month after birth, and die after 2 months [ 17 ]. Akt/protein kinase B (PKB) cancer metastasis epithelial–mesenchymal transition (EMT) mitogen-activated protein kinase (MAPK) Twist...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 58–66.
Published: 19 January 2012
...-early gene mitogen-activated protein kinase (MAPK) ternary complex factor (TCF) FOS was initially identified as a gene that is very rapidly induced upon treatment of mammalian cells with serum or growth factors without the need for new protein synthesis [ 1 – 3 ]. The latter property...
Articles
Ahmed Lawan, Emma Torrance, Sameer Al-Harthi, Muhannad Shweash, Sulaiman Alnasser, Thikryat Neamatallah, Juliane Schroeder, Robin Plevin
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 235–239.
Published: 19 January 2012
...-specificity phosphatase (DUSP) immunity mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase phosphatase 2 (MKP-2) phosphatase proliferation The explosion in the delineation of intracellular kinase signalling pathways in the last 25 years has been exemplified by study...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 230–234.
Published: 19 January 2012
... of the dimeric complex to specific target genes. activating transcription factor 2 (ATF2) activating transcription factor 7 (ATF7) activator protein 1 (AP-1) c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase (MAPK) p38 In contrast with its role in promoting melanoma...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 85–89.
Published: 19 January 2012
...) mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase kinase 4 (MKK4) mitogen-activated protein kinase kinase 7 (MKK7) neurodegeneration Cells have the ability to communicate with each other and modify their behaviour according to changes in their environment. The information...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 139–146.
Published: 19 January 2012
... at low physiological doses of growth factors, such as EGF (epidermal growth factor). 26 5 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 Akt cross-talk mitogen-activated protein kinase (MAPK) phosphoinositide 3-kinase (PI3K) Ras 1 To whom...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 224–229.
Published: 19 January 2012
... microscopy mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase/extracellular-signal-regulated kinase kinase (MEK) nuclear accumulation 1 To whom correspondence should be addressed (email [email protected] ). A further question is how a cell generates appropriate ERK...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (2): 684–687.
Published: 22 March 2011
... 2011 activating transcription factor 4 (ATF4) acute myeloid leukaemia (AML) cell signalling genome-wide association study (GWAS) mitogen-activated protein kinase (MAPK) tribbles AML acute myeloid leukaemia ATF4 activating transcription factor 4 C/EBP CCAAT/enhancer...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (5): 1257–1264.
Published: 24 September 2010
... points of study. 1 To whom correspondence should be addressed (email [email protected] ). 10 3 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 mitogen-activated protein kinase (MAPK) Saccharomyces cerevisiae signal integration signal...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (4): 1027–1032.
Published: 26 July 2010
[email protected] ). 8 1 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 embryonic stem cell glycogen synthase kinase 3 (GSK3) ground state mitogen-activated protein kinase (MAPK) pluripotency signalling Mouse ES (embryonic stem) cells are derived from the ICM...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (6): 1254–1259.
Published: 19 November 2009
... cytoplasmic enzymes to transcription factors [ 3 ]. angiogenesis big mitogen-activated protein kinase 1 (BMK1) endothelial cell extracellular-signal-regulated kinase 5 (ERK5) mitogen-activated protein kinase (MAPK) signal transduction © The Authors Journal compilation © 2009 Biochemical...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (4): 824–829.
Published: 22 July 2009
... obstructive pulmonary disease (COPD) corticosteroid mitogen-activated protein kinase (MAPK) steroid theophylline Asthma is a common chronic inflammatory disease and afflicts approx. 300 million people worldwide [ 1 ]. Asthma accounts for ∼1 out of every 250 deaths worldwide and also has profound...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (1): 237–241.
Published: 20 January 2009
... circumstances, as transporter-like sensors (or ‘transceptors’) upstream of mTOR. 1 email [email protected] 12 9 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 amino acid transporter general control non-derepressible (GCN) mitogen-activated protein...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (1): 273–277.
Published: 20 January 2009
... [email protected] 18 11 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 mitogen-activated protein kinase (MAPK) mitotic commitment nutrient stress Polo kinase target of rapamycin (TOR) yeast The control of mitotic commitment through stress...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (5): 1097–1101.
Published: 19 September 2008
... ]. mitogen-activated protein kinase (MAPK) mitosis-promoting factor (MPF) mitotic commitment Polo kinase spindle pole body (SPB) yeast Extensive genetic analysis in the fission yeast, Schizosaccharomyces pombe , and biochemical manipulations of frog and sea-urchin eggs led to a core...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (3): 442–445.
Published: 22 May 2007
... 12 2006 © 2007 Biochemical Society 2007 chylomicron remnant-like particle cyclo-oxygenase (COX) endothelial cell haem oxygenase-1 (HO-1) mitogen-activated protein kinase (MAPK) prostanoid EC (endothelial cell) dysfunction is characterized by impairment of endothelial...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 837–841.
Published: 25 October 2006
... [email protected] 27 6 2006 © 2006 The Biochemical Society 2006 docking site mitogen-activated protein kinase (MAPK) scaffold protein Ste7 yeast Specificity in cellular signal transduction is achieved by multiple mechanisms. First and foremost, as in all other cellular...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 833–836.
Published: 25 October 2006
... of Ras (KSR) mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase/extracellular-signal-regulated kinase kinase (MEK) scaffold Signal transduction networks enable alterations in the extracellular environment to be transmitted to the inside of the cell. The ubiquitous MAPK...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 828–832.
Published: 25 October 2006
... kinase (JNK)-interacting protein (JIP) mitogen-activated protein kinase (MAPK) scaffold protein As well as recruiting JNK activators (i.e. MLK and MKK7), JIP proteins also recruit negative regulators of JNK. For example, JIP1 and JIP2 selectively associate with the JNK-specific MKPs, MKP7...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (6): 1018–1023.
Published: 25 October 2006
... (email [email protected] ). 22 6 2006 © 2006 The Biochemical Society 2006 cytokine dual-specificity phosphatase (DUSP) glucocorticoid inflammation innate immune response mitogen-activated protein kinase (MAPK) The MAPKs are components of intracellular signalling...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 842–845.
Published: 25 October 2006
... 1 To whom correspondence should be addressed (email [email protected] ). 25 7 2006 © 2006 The Biochemical Society 2006 binding partner extracellular-signal-regulated kinase (ERK) mitogen-activated protein kinase (MAPK) nuclear export phosphorylation protein...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (5): 1158–1161.
Published: 26 October 2005
... correspondence should be addressed (email [email protected] ). 3 6 2005 © 2005 The Biochemical Society 2005 anionic phospholipid β-1,3-glucan cardiolipin (CL) cell wall biogenesis mitochondrion mitogen-activated protein kinase (MAPK) Cardiolipin (CL) is an acidic...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2003) 31 (6): 1171–1177.
Published: 01 December 2003
... of Essex, Colchester, 2–4 July 2003 10 June 2003 © 2003 Biochemical Society 2003 angiogenesis Flt1 kinase-insert-domain-containing receptor (KDR) mitogen-activated protein kinase (MAPK) survival vascular endothelial growth factor (VEGF) Abbreviations used: eNOS...
Articles
M. M. Manson, K. A. Holloway, L. M. Howells, E. A. Hudson, S. M. Plummer, M. S. Squires, S. A. Prigent
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (2): 7–12.
Published: 01 February 2000
...-dependent kinase apoptosis curcumin epigallocatechin gallate (EGCG) mitogen-activated protein kinase (MAPK) nuclear factor kB (NF-kB) Chemoprotection Modulation of signal-transduction pathways by chemopreventive agents M. M. Manson K. A. Holloway*, L. M. Howelk*, E. A. Hudson*, S. M. Plummer...
