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1-29 of 29
Keywords: mitogen-activated protein kinase (MAPK)
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (5): 1069–1074.
Published: 09 October 2015
... ]. © 2015 Authors; published by Portland Press Limited 2015 chronic inflammation disease mitogen-activated protein kinase (MAPK) tribbles The TRIB (tribbles) family of genes encode a group of highly conserved psuedokinase proteins which act as adaptors and regulate key inflammatory...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (5): 1104–1107.
Published: 09 October 2015
... Limited 2015 acute myeloid leukaemia (AML) CCAAT/enhancer binding protein (C/EBP) haematopoiesis mitogen-activated protein kinase (MAPK) tribbles homolog 1 (Trib1) Pseudokinase proteins modulate multiple signalling pathways by interacting as kinase decoys or modulating proteasome-related...
Articles
Gopika N. Nithianandarajah-Jones, Bettina Wilm, Christopher E.P. Goldring, Jürgen Müller, Michael J. Cross
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (6): 1584–1589.
Published: 17 November 2014
...Gopika N. Nithianandarajah-Jones; Bettina Wilm; Christopher E.P. Goldring; Jürgen Müller; Michael J. Cross Extracellular-signal-regulated kinase 5 (ERK5), also termed big MAPK1 (BMK1), is the most recently discovered member of the mitogen-activated protein kinase (MAPK) family. It is expressed...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (1): 11–24.
Published: 23 January 2014
... within the greater context of the field. 1 email [email protected] 26 6 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 inhibitor of nuclear factor κB kinase (IKK) innate immunity mitogen-activated protein kinase (MAPK) phosphoinositide 3-kinase...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (4): 987–994.
Published: 18 July 2013
... 2013 Ca 2+ /calmodulin-activated serine kinase (CASK) human epidermal growth factor receptor 3 (Her3) kinase suppressor of Ras (KSR) mitogen-activated protein kinase (MAPK) extracellular-signal-regulated kinase pseudokinase Raf 1 email [email protected] 11 6 2013...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 85–89.
Published: 19 January 2012
... signalling in diseases and how pharmacological inhibition of JNK activation, rather than JNK activity, may be a potential therapeutic strategy that avoids the unwanted side effects associated with direct targeting of JNK isoforms. cancer c-Jun N-terminal kinase (JNK) mitogen-activated protein...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 139–146.
Published: 19 January 2012
... 5 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 Akt cross-talk mitogen-activated protein kinase (MAPK) phosphoinositide 3-kinase (PI3K) Ras A cell in an organism is immersed in an ocean of growth factors and hormones, yet how signalling networks...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 224–229.
Published: 19 January 2012
... regression [ 19 ]. 26 7 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 extracellular-signal-regulated kinase (ERK) high content microscopy mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase/extracellular-signal-regulated kinase kinase...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 230–234.
Published: 19 January 2012
... transcription factor 7 (ATF7) activator protein 1 (AP-1) c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase (MAPK) p38 Among the ATF (activating transcription factor) family, ATF2 and ATF7 are structurally very similar, especially within the bZIP (basic region/leucine zipper) DNA-binding...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 90–93.
Published: 19 January 2012
... 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 Akt/protein kinase B (PKB) cancer metastasis epithelial–mesenchymal transition (EMT) mitogen-activated protein kinase (MAPK) Twist phosphorylation transforming growth factor β receptor signalling (TGFβR signalling...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 58–66.
Published: 19 January 2012
... no clear mechanistic explanation of why acetylation turnover is important. E26-like kinase 1 (ELK1) FOS immediate-early gene mitogen-activated protein kinase (MAPK) ternary complex factor (TCF) FOS was initially identified as a gene that is very rapidly induced upon treatment...
Articles
Ahmed Lawan, Emma Torrance, Sameer Al-Harthi, Muhannad Shweash, Sulaiman Alnasser, Thikryat Neamatallah, Juliane Schroeder, Robin Plevin
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 235–239.
Published: 19 January 2012
... (University of Strathclyde, U.K.), Colin Taylor (Cambridge, U.K.), Alan Wallace (AstraZeneca, U.K.) and Stephen Yarwood (Glasgow, U.K.). cancer dual-specificity phosphatase (DUSP) immunity mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase phosphatase 2 (MKP-2) phosphatase...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (2): 684–687.
Published: 22 March 2011
... controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways J. Biol. Chem. 2007 282 18379 18387 38 Sung H.Y. Francis S. Crossman D.C. Kiss-Toth E. Tribbles-1, a mitogen activated protein kinase (MAPK) scaffold regulates inflammation in vascular...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (5): 1257–1264.
Published: 24 September 2010
... points of study. 1 To whom correspondence should be addressed (email [email protected] ). 10 3 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 mitogen-activated protein kinase (MAPK) Saccharomyces cerevisiae signal integration signal...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (4): 1027–1032.
Published: 26 July 2010
... mitogen-activated protein kinase (MAPK) pluripotency signalling Figure 2 Strain differences in sensitivity to MAPK activity Number of mixed (partially alkaline-phosphatase-negative) and undifferentiated colonies formed from 600 129-, C57Bl6 (B6)-, CBA- or FVB-ES cells plated in N2B27 plus LIF...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (6): 1254–1259.
Published: 19 November 2009
...) endothelial cell extracellular-signal-regulated kinase 5 (ERK5) mitogen-activated protein kinase (MAPK) signal transduction MAPKs (mitogen-activated protein kinases) play an essential role in regulating many cellular processes including growth, differentiation and apoptosis. MAPKs are activated...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (4): 824–829.
Published: 22 July 2009
... 2009 Biochemical Society 2009 asthma chronic obstructive pulmonary disease (COPD) corticosteroid mitogen-activated protein kinase (MAPK) steroid theophylline Asthma is a common chronic inflammatory disease and afflicts approx. 300 million people worldwide [ 1 ]. Asthma accounts...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (1): 237–241.
Published: 20 January 2009
... circumstances, as transporter-like sensors (or ‘transceptors’) upstream of mTOR. 1 email [email protected] 12 9 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 amino acid transporter general control non-derepressible (GCN) mitogen-activated protein...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (1): 273–277.
Published: 20 January 2009
... [email protected] 18 11 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 mitogen-activated protein kinase (MAPK) mitotic commitment nutrient stress Polo kinase target of rapamycin (TOR) yeast Rapamycin inhibition of TOR signalling activates...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (5): 1097–1101.
Published: 19 September 2008
...) and MAPK networks to the activation of MPF to regulate the timing of cell division. 1 email [email protected] 17 3 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 mitogen-activated protein kinase (MAPK) mitosis-promoting factor (MPF) mitotic...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (3): 442–445.
Published: 22 May 2007
...) endothelial cell haem oxygenase-1 (HO-1) mitogen-activated protein kinase (MAPK) prostanoid EC (endothelial cell) dysfunction is characterized by impairment of endothelial-dependent vasodilatation and by the prevalence of both pro-inflammatory and pro-coagulant events in the endothelium [ 1...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 828–832.
Published: 25 October 2006
... kinase (JNK)-interacting protein (JIP) mitogen-activated protein kinase (MAPK) scaffold protein JIP1 was initially characterized as an inhibitor of JNK signalling due to the observation that when overexpressed in cells it prevented JNK from phosphorylating its nuclear substrates such as c-Jun...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 842–845.
Published: 25 October 2006
... 2006 The Biochemical Society 2006 binding partner extracellular-signal-regulated kinase (ERK) mitogen-activated protein kinase (MAPK) nuclear export phosphorylation protein phosphatase The ‘classical’ Ras/MAPK pathway containing ERK1 (extracellular-signal-regulated kinase 1) and ERK2...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (6): 1018–1023.
Published: 25 October 2006
... to eventual termination of the signal. cytokine dual-specificity phosphatase (DUSP) glucocorticoid inflammation innate immune response mitogen-activated protein kinase (MAPK) The MAPKs are components of intracellular signalling pathways that control a vast array of cellular processes, one...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 833–836.
Published: 25 October 2006
... studies that will further elucidate the roles of these important regulatory molecules. 1 email [email protected] . 29 6 2006 © 2006 The Biochemical Society 2006 growth factor IQGAP1 kinase suppressor of Ras (KSR) mitogen-activated protein kinase (MAPK...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 837–841.
Published: 25 October 2006
... 2006 docking site mitogen-activated protein kinase (MAPK) scaffold protein Ste7 yeast Specificity in cellular signal transduction is achieved by multiple mechanisms. First and foremost, as in all other cellular processes, the pre-eminent mechanism of biochemical specificity...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (5): 1158–1161.
Published: 26 October 2005
... in [ 21 ]). © 2005 The Biochemical Society 2005 anionic phospholipid β-1,3-glucan cardiolipin (CL) cell wall biogenesis mitochondrion mitogen-activated protein kinase (MAPK) Cardiolipin (CL) is an acidic glycerophospholipid with a unique dimeric structure consisting of four fatty...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2003) 31 (6): 1171–1177.
Published: 01 December 2003
... of Essex, Colchester, 2–4 July 2003 10 June 2003 © 2003 Biochemical Society 2003 angiogenesis Flt1 kinase-insert-domain-containing receptor (KDR) mitogen-activated protein kinase (MAPK) survival vascular endothelial growth factor (VEGF) Abbreviations used: eNOS...
Articles
M. M. Manson, K. A. Holloway, L. M. Howells, E. A. Hudson, S. M. Plummer, M. S. Squires, S. A. Prigent
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (2): 7–12.
Published: 01 February 2000
...-dependent kinase apoptosis curcumin epigallocatechin gallate (EGCG) mitogen-activated protein kinase (MAPK) nuclear factor kB (NF-kB) Chemoprotection Modulation of signal-transduction pathways by chemopreventive agents M. M. Manson K. A. Holloway*, L. M. Howelk*, E. A. Hudson*, S. M. Plummer...
