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Keyword: molecular chaperones
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Biochem Soc Trans (2019) BST20180496.
Published: 26 November 2019
... SAGA and NuA4/TIP60 complex assembly and recruitment to chromatin. We further discuss its evolutionary history within the PIKK family and highlight recent findings that reveal the importance of molecular chaperones in pseudokinase folding, function, and conservation. Correspondence: Dominique...
Biochem Soc Trans (2019) BST20190334.
Published: 22 November 2019
... isomerization of peptidyl-prolyl peptide bonds in unfolded and partially folded polypeptide chains and native state proteins. Originally, both proteins have been studied as molecular chaperones belonging to the steroid receptor heterocomplex, where they were first discovered. In addition to their expected role...
Biochem Soc Trans (2017) 45 (1): 251-260.
Published: 15 February 2017
...Carol V. Robinson Twenty-five years ago, we obtained our first mass spectra of molecular chaperones in complex with protein ligands and entered a new field of gas-phase structural biology. It is perhaps now time to pause and reflect, and to ask how many of our initial structure predictions and...