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Keywords: mouse models
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Articles
Biochem Soc Trans (2018) 46 (3): 669–681.
Published: 21 May 2018
... in a tissue-specific manner. In this review, we summarise the existing nesprin mouse models, compare their phenotypes and discuss the potential mechanisms underlying nesprin-associated diseases. Correspondence: Qiuping Zhang ( qp.zhang@kcl.ac.uk ) 6 2 2018 5 4 2018 20 4 2018...
Articles
Biochem Soc Trans (2016) 44 (5): 1483–1490.
Published: 19 October 2016
... Attribution License 4.0 (CC BY) . gene therapy mitochondria mitochondrial dysfunction mouse models therapeutics The main function of mitochondria is to convert the energy derived from nutrients into heat and ATP, a high-energy molecule exploited by the cell biochemical machineries. This...
Articles
Biochem Soc Trans (2005) 33 (4): 689–693.
Published: 01 August 2005
... damage DNA mismatch repair (MMR) mouse models HNPCC (hereditary non-polyposis colon cancer) is a highly penetrant, autosomal dominant cancer syndrome, characterized by early onset of colorectal cancers. It is estimated that HNPCC accounts for 5% of all colorectal cancers. In addition to cancers...