... biological networks gene expression and regulation intrinsically disordered proteins multifunctional proteins nucleoporins The canonical role of FG-Nups is to constitute a selective permeability barrier in the central channel of the NPC. This barrier serves as a programmed gate for molecule...

... enzyme function moonlighting proteins multifunctional proteins protein function trigger enzymes In the 1980's, Piatigorsky and coworkers made the somewhat surprising discovery that several soluble enzymes that had evolved over billions of years to perform a specific catalytic function have...