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Keywords: multivesicular body (MVB)
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Articles
Biochem Soc Trans (2011) 39 (2): 559–562.
Published: 22 March 2011
... of Nature's concept to cope with malfunctions. 1 To whom correspondence should be addressed (email margot.zoeller@uni-heidelberg.de ). 31 8 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 exosome multivesicular body (MVB) protein kinase C (PKC) target...
Articles
Biochem Soc Trans (2010) 38 (6): 1413–1416.
Published: 24 November 2010
... Biochemical Society 2010 endocytosis endosome lysosome multivesicular body (MVB) Lysosomes act as the terminal compartment of the endocytic and autophagic pathways ( Figure 1 ). It is now recognized that the delivery of endocytosed and autophagocytosed macromolecules to lysosomes...
Articles
Biochem Soc Trans (2009) 37 (1): 156–160.
Published: 20 January 2009
... required for transport III (ESCRT-III) vacuolar protein sorting 4 (VPS4) multivesicular body (MVB) ESCRTs (endosomal sorting complexes required for transport) 0, I, II and III, first discovered in Saccharomyces cerevisiae , catalyse receptor sorting at endosomal membranes into vesicles that bud...
Articles
Biochem Soc Trans (2009) 37 (1): 146–150.
Published: 20 January 2009
...) endosome epidermal growth factor receptor (EGFR) His domain phosphotyrosine phosphatase (HD-PTP) multivesicular body (MVB) Down-regulation of mitogenic tyrosine kinase receptors is a process of fundamental importance, since defective receptor down-regulation results in a failure to turn off...
Articles
Biochem Soc Trans (2009) 37 (1): 151–155.
Published: 20 January 2009
... required for transport (ESCRT) lysosome multivesicular body (MVB) protein sorting Endosomes facilitate transport of membrane proteins between the plasma membrane, the trans -Golgi network and the lysosome/vacuole [ 1 ]. Sorting to the lysosome/vacuole compartment involves late endosomal...
Articles
Biochem Soc Trans (2009) 37 (1): 208–212.
Published: 20 January 2009
.... Roles of ESCRT in autophagy-associated neurodegeneration Autophagy 2008 4 230 232 autophagy charged multivesicular body protein 2B (CHMP2B) endosomal sorting complex required for transport III (ESCRT-III) endosome frontotemporal dementia (FTD) multivesicular body (MVB) FTD3...
Articles
Biochem Soc Trans (2009) 37 (1): 143–145.
Published: 20 January 2009
...@mayo.edu ). 18 7 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 ATPase associated with various cellular activities (AAA) endosomal sorting complex required for transport (ESCRT) multivesicular body (MVB) vacuolar protein sorting 4 (Vps4) The endosomal...
Articles
Biochem Soc Trans (2009) 37 (1): 167–172.
Published: 20 January 2009
... complex required for transport (ESCRT) endosome multivesicular body (MVB) neurodegeneration pathogenesis The endocytic down-regulation of numerous signalling receptors such as the EGFR (epidermal growth factor receptor) plays an important role in modulating the amplitude and kinetics...
Articles
Biochem Soc Trans (2009) 37 (1): 195–199.
Published: 20 January 2009
... for transport (ESCRT) multivesicular body (MVB) retrovirus tumour susceptibility gene 101 (Tsg101) vacuolar protein sorting 4 (Vps4) virus The ESCRT machinery comprises the protein products of the Class E subset of Vps (vacuolar protein sorting) genes, identified as being required for sorting...
Articles
Biochem Soc Trans (2009) 37 (1): 173–177.
Published: 20 January 2009
... epidermal growth factor receptor (EGFR) endosomal sorting complex required for transport (ESCRT) multivesicular body (MVB) phosphoinositide 3-kinase (PI3K) protein tyrosine phosphatase 1B (PTP1B) EGF (epidermal growth factor) binding to the EGFR (EGF receptor) promotes increased RTK (receptor...
Articles
Biochem Soc Trans (2009) 37 (1): 178–180.
Published: 20 January 2009
... multivesicular body (MVB) MHC class I In mammalian cells, many endocytosed cell-surface proteins, including receptors and bound ligands, are internalized via clathrin-coated pits and transferred successively to early endosomes and late endosomes before delivery to lysosomes for degradation by proteases...
Articles
Biochem Soc Trans (2008) 36 (5): 791–796.
Published: 19 September 2008
... Journal compilation © 2008 Biochemical Society 2008 E3 adaptor endocytosis multivesicular body (MVB) Rsp5p membrane protein trafficking yeast Ubiquitination was initially described as promoting proteasomal degradation, and has since been shown to regulate other processes, including DNA...