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Keywords: nanobody
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Articles
Targeting small GTPases and their downstream pathways with intracellular macromolecule binders to define alternative therapeutic strategies in cancer
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2021–2035.
Published: 08 October 2021
... on behalf of the Biochemical Society 2021 cancer DARPin intracellular antibody nanobody small GTPases targeted protein degradation The RAS superfamily of small GTPases includes the RAS, RAB, ARF, RHO and RAN families. Many of these GTPases switch between an inactive GDP-bound state...
