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Keywords: necroptosis
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Biochem Soc Trans (2023) 51 (1): 303–313.
Published: 25 January 2023
...Xiaohui Wang; Larisa I. Labzin Programmed cell death is a critical host defence strategy during viral infection. Neighbouring cells deal with this death in distinct ways depending on how the infected cell dies. While apoptosis is considered immunologically silent, the lytic pathways of necroptosis...
Biochem Soc Trans (2022) 50 (6): 1583–1594.
Published: 24 November 2022
... inflammatory signalling or inducing programmed cell death activation, ranging from apoptosis, pyroptosis to necroptosis. In this review, we first discuss the mechanisms by which RIPK1 and RIPK3 promote the assembly of death-inducing complexes and how these cell death pathways are activated as host responses...
Biochem Soc Trans (2022) 50 (4): 1197–1205.
Published: 30 August 2022
... kinase (RIPK) 1, RIPK3, Z-DNA-binding protein 1 (ZBP1), and TIR domain-containing adapter-inducing IFN-β (TRIF), which are all major players in necroptosis, a distinct form of regulated cell death. Necroptosis is mostly presumed to be a fail-safe form of cell death, occurring in cells in which apoptosis...
Biochem Soc Trans (2022) 50 (1): 13–20.
Published: 15 February 2022
... can contribute to autoinflammatory and autoimmune diseases or life-threatening conditions like sepsis. These diseases generally display increased levels of cell death, which, downstream of the TNF receptor, can either be caspase-dependent (apoptosis) or caspase-independent (necroptosis). Significant...
Biochem Soc Trans (2021) 49 (2): 793–804.
Published: 12 April 2021
... & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with CAUL. apoptosis cell clearance necroptosis necrosis phagocytosis pyroptosis Apoptosis is largely driven by one of two pathways: the intrinsic/mitochondrial pathway and the extrinsic...