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Keywords: neurofibrillary tangle (NFT)
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Articles
Modulation of tau pathology in tau transgenic models
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (4): 996–1000.
Published: 26 July 2010
... in APP/PS1×TauKO mice. 1 To whom correspondence should be addressed (email [email protected] ). 11 1 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 Alzheimer's disease amyloid neurofibrillary tangle (NFT) tau tauopathy toxicity AD...
Articles
Deletion of murine tau gene increases tau aggregation in a human mutant tau transgenic mouse model
Available to PurchaseKunie Ando, Karelle Leroy, Céline Heraud, Anna Kabova, Zehra Yilmaz, Michèle Authelet, Valèrie Suain, Robert De Decker, Jean-Pierre Brion
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (4): 1001–1005.
Published: 26 July 2010
... the same propensity for aggregation. Alzheimer's disease neurofibrillary tangle (NFT) paired helical filament tau (PHF-tau) tau tau knockout tau transgenic mouse AD is neuropathologically characterized by senile plaques and NFTs (neurofibrillary tangles). Senile plaques are composed...
Articles
Pathways linking Aβ and tau pathologies
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (4): 993–995.
Published: 26 July 2010
...) neurofibrillary tangle (NFT) tau Aβ has been the central focal point of AD research for over a decade, and, as indicated above, is generally considered to be the upstream causative factor. Aβ can exist in several different physical states and compartments (i.e. monomeric, oligomeric or fibrillar...
