... acetylcholine receptor will be reviewed. 1 To whom correspondence should be addressed (email carla.molteni@kcl.ac.uk ). 22 9 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 pentameric ligand-gated ion channels GABA receptors 5-HT 3 receptor nicotinic...

... of human recombinant homomeric and heteromeric 5-HT 3 receptors are markedly different, being <1 and approx. 16 pS respectively. Paradoxically, from the results of studies performed on the closely related nicotinic acetylcholine receptor, the channel-lining M2 domain of the 5-HT 3A subunit is predicted...

...N.S. Millar Nicotinic acetylcholine receptors (nAChRs) are a diverse family of neurotransmitter-gated ion channels which contain five transmembrane subunits arranged around a central pore. Distinct receptor subtypes are expressed at the vertebrate skeletal neuromuscular junction, in mechanosensory...