... with type III immunity are nucleases, which aid in defense by promiscuously degrading both self and non-self nucleic acids. Although more research is needed, it appears that most of these systems operate as an altruistic mechanism to protect the population by inducing cell dormancy or cell death...

.... The possible in vivo targets, as well as our current knowledge of the Cmr complex, is reviewed in the present paper. clustered regularly interspaced short palindromic repeats (CRISPR) Cmr repeat-associated mysterious protein (RAMP) RNA interference metal ion nuclease 1 email scbailey...

... pathway has been determined, factors that facilitate this and/or function in quality control of the RNA are poorly understood. In the present paper, the SRP assembly pathway is summarized, and evidence for the involvement of both the Rex1p and nuclear exosome nucleases and the TRAMP (Trf4–Air2–Mtr4p...

...David M.J. Lilley Four-way DNA (Holliday) junctions are resolved into duplex species by the action of the junction-resolving enzymes, nucleases selective for the structure of helical branchpoints. These have been isolated from bacteria and their phages, archaea, yeasts and mammals, including humans...

... (topoisomerase IIB). This degradation, termed sperm chromatin fragmentation, can be reversed by EDTA, which causes TOP2B to religate the double-stranded breaks it originally produced. Under certain conditions, a nuclease then degrades the sperm DNA further, digesting the entire sperm genome. When mouse...