... a short period around fertilization, the nucleoli in oocytes and embryos transform into ribosome-biosynthesis-inactive structures termed nucleolus-like or nucleolus precursor bodies (NPBs). For decades, researchers considered these structures to be passive repositories of nucleolar proteins used...

... and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . cancer gene regulation non-coding RNA nucleolus ribosomopathies Ribosome biogenesis is the essential, complex, and tightly regulated process in which large and small ribosomal subunits are assembled...

... discuss the involvement of ribosome biogenesis in the homoeostasis of p53 in the cell and in human health and disease. 12 4 2016 MDM2 nucleolus p53 ribosome ribosomal protein 5S RNP © 2016 The Author(s) 2016 This is an open access article published by Portland Press Limited...

...Tina McLeod; Akilu Abdullahi; Min Li; Saverio Brogna The nucleolus is the most prominent morphological feature within the nucleus of eukaryotic cells and is best known for its role in ribosome biogenesis. It forms around highly transcribed ribosomal RNA gene repeats which yield precursor rRNAs...

.... The nucleolus today J. Cell Sci. 1991 99 465 471 39 Masson C. Andre C. Arnoult J. Geraud G. Hernandez-Verdun D. A 116,000 Mr nucleolar antigen specific for the dense fibrillar component of the nucleoli J. Cell Sci. 1990 95 371 381 40 Kill I.R. Localisation...

...J.-L. Prieto; B. McStay The nucleolus is the site of rRNA transcription, pre-rRNA processing and ribosome subunit assembly. The nucleolus assembles around clusters of ribosomal gene repeats during late telophase, persists throughout interphase and then disassembles as cells enter mitosis...

...S.H. Kim; E.V. Ryabov; J.W.S. Brown; M. Taliansky The nucleolus is a prominent subnuclear domain and is classically regarded as the site of transcription of rRNA, processing of the precursor rRNAs and biogenesis of pre-ribosomal particles. In addition to these traditionally recognized activities...

... genetic disease HIV nucleolus DMPK, dystrophica myotonica-protein kinase MDM2, murine double minute 2 Ribozymes and RNA Catalysis: Focused Meeting Organized by D. M. J. Lilley (Department of Biochemistry, University of Dundee) and F. Eckstein (Max-Planck Institute for Experimental...