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Biochem Soc Trans (2009) 37 (4): 615–626.
Published: 22 July 2009
... of the catalytic cycle of the enzymes. 1 To whom correspondence should be addressed (email [email protected] ). 25 3 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 cancer p85 p110 phosphoinositide 3-kinase (PI3K) phosphoinositide 3,4,5-trisphosphate...
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Biochem Soc Trans (2007) 35 (2): 245–249.
Published: 20 March 2007
... target of rapamycin (mTOR) p110 phosphatidylinositol phosphoinositide 3-kinase (PI3K) The discovery of the pan-specific PI3K inhibitors wortmannin and LY294002 was a critical early event that enabled the rapid exploration of PI3K signalling. Wortmannin is a fungal natural product...
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Biochem Soc Trans (2004) 32 (2): 320–325.
Published: 01 April 2004
... in Signalling and Disease, a Biochemical Society Focused Meeting held at Novartis Horsham Research Centre, U.K., 11–12 November 2003 22 October 2003 © 2004 Biochemical Society 2004 Bcl-xL Bruton's tyrosine kinase (Btk) nuclear factor-κB (NF-κB) p85 p110 Xid Abbreviations...