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Keywords: paired helical filament tau (PHF-tau)
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Articles
Deletion of murine tau gene increases tau aggregation in a human mutant tau transgenic mouse model
Available to PurchaseKunie Ando, Karelle Leroy, Céline Heraud, Anna Kabova, Zehra Yilmaz, Michèle Authelet, Valèrie Suain, Robert De Decker, Jean-Pierre Brion
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (4): 1001–1005.
Published: 26 July 2010
... the same propensity for aggregation. Alzheimer's disease neurofibrillary tangle (NFT) paired helical filament tau (PHF-tau) tau tau knockout tau transgenic mouse AD is neuropathologically characterized by senile plaques and NFTs (neurofibrillary tangles). Senile plaques are composed...
