... treatment options continue to be available. The intra-erythrocytic stage of the malaria parasite's life cycle is dependent on an extracellular supply of pantothenate (vitamin B 5 ), the precursor of CoA (coenzyme A). It has been known for many years that proliferation of the parasite during this stage...

...Philippe Naquet; Giuseppina Pitari; Sylvestro Duprè; Franck Galland Pantetheinase is an ubiquitous enzyme which hydrolyses D -pantetheine into cysteamine and pantothenate (vitamin B 5 ) on the dissimilative pathway of CoA. Pantetheinase isoforms are encoded by the Vnn (vanin) genes and Vnn1...

... of species in complex mixtures [ 39 – 41 ]. anti-metabolite coenzyme A (CoA) neurodegeneration pantothenate protein acetylation vanin Anyone who took a first year undergraduate biochemistry course will (hopefully!) recall that coenzyme A (CoA) is a ubiquitous coenzyme which functions...

...C.M.C. Lobley; F. Schmitzberger; M.L. Kilkenny; H. Whitney; H.H. Ottenhof; E. Chakauya; M.E. Webb; L.M. Birch; K.L. Tuck; C. Abell; A.G. Smith; T.L. Blundell Pantothenate is synthesized in bacteria, fungi and plants, and as vitamin B5 is a dietary requirement in animals. The three-dimensional...