... infection mycology pathogenesis Fungal pathogens (i.e. fungal organisms able to cause disease in a given host) are of high relevance for human health, affecting annually a billion people and causing 1.5 million deaths worldwide [ 1 ]. In addition, they are a threat to food crops [ 2 ] and other...

... by the cellular phosphatase, calcineurin. This review provides the current state-of-the-art knowledge about the molecular controls of cell fusion-dependent pathogenesis caused by VZV. Correspondence: Stefan L. Oliver ( [email protected] ) 27 9 2020 30 10 2020 3 11 2020 © 2020...

... to elucidate pathogenesis mechanisms of Bp , little is known about how a harmless soil bacterium adapts to different environmental conditions, in particular, the shift to a human host to become a highly virulent pathogen. The bacterium has a large genome encoding an armory of factors that assist the pathogen...

... regulator of PCD in B. cinerea and that proper regulation of the host-induced PCD is essential for pathogenesis in this and other similar fungal pathogens. Bir1p belongs to the type-II (IAP-like) BIR-containing proteins, which also includes the mammalian survivin/BIRC5. As mentioned, IAPs are anti...

... metabolites in various cell types has shed light on mechanisms of disease pathogenesis and may pave the way for future development of new therapies for these LSDs. 1 To whom correspondence should be addressed (email [email protected] ). 10 5 2010 © The Authors Journal...

.... Important discoveries linking the metabolism of M. tuberculosis and pathogenesis has renewed interest in this area of research. Previous experimental studies were limited to the analysis of individual genes or enzymes, whereas recent advances in computational systems biology and high-throughput experimental...

... established and are key to our understanding of the pathogenic mechanisms in COPD and may be important for the development of new therapies. There is a relationship between chronic inflammatory diseases and aging, and the processes involved in aging may provide a novel mechanism in the pathogenesis of COPD...

... been shown to cause ALS (amyotrophic lateral sclerosis) [ 30 ]. cancer endosomal sorting complex required for transport (ESCRT) endosome multivesicular body (MVB) neurodegeneration pathogenesis The endocytic down-regulation of numerous signalling receptors such as the EGFR (epidermal...

... of these enzymes and their potential as therapeutic targets. Aβ catabolism Alzheimer's disease endothelin-converting enzyme neprilysin pathogenesis therapeutic intervention 1 To whom correspondence should be addressed (email [email protected] ). 28 7 2005 © 2005 The Biochemical...

... July 2002 Copyright 2003 Biochemical Society 2003 pathogenesis pathogen evolution type III system Abbreviations used: Hms, haemin storage. 104 Biochemical Society Transactions (2003) Volume 31, part 1 Yersinia pestis and plague R.W. Titball*1, J. Hill*, D.G. Lawton and K.A...