... peroxins (Pexs) regulate glycosome and peroxisome homeostasis that is governed by multiple processes including ( Figure 1 ): (i) organelle formation and maturation, (ii) protein import, (iii) proliferation via fission, and (iv) degradation of non-functional or unnecessary organelles via autophagy...

... Society 2010 myosin β-oxidation peroxin photorespiration protein import receptor The development of in vivo imaging techniques has led to a growing appreciation that organelles are extremely dynamic, often pleomorphic, and motile structures (see Supplementary Movie S1 at http...

..., but our understanding of the molecular function of Pex1p and Pex6p, the second AAA peroxin in peroxisomal biogenesis [ 6 ], remained incomplete for many years. Peroxisomes are single-membrane-bound organelles of virtually all eukaryotic cells, which display a unique variability in their enzyme content...

... (ATPase associated with various cellular activities) peroxins, Pex1p and Pex6p, are encoded by PEX1 and PEX6 , the causal genes for CG (complementation group) 1 and CG4 PBDs respectively. PEX26 , which is responsible for CG8 PBDs, codes for Pex26p, the recruiter of Pex1p–Pex6p complexes to peroxisomes. We...

... cholesterol peroxin phytanic acid pristanic acid Zellweger syndrome DHA, docosahexaenoic acid ER, endoplasmic reticulum 2HPCL, 2-hydroxyphytanoyl-CoA lyase MFP, multifunctional protein PBD, peroxisome biogenesis disorder Pex, peroxin PTS, peroxisome targeting signal RCDP, rhizomelic...