... [e.g. the protein kinase C (PKC) C2 domain] or a Ca 2+ -independent manner, e.g. the phosphatase and tensin homologue deleted on chromosome 10 (PTEN) C2 domain [ 35 ]. Both types of C2 domains have been shown to interact with anionic lipids with different specificities and/or to co-ordinate...

.... Pomeranz K.M. Erneux C. A small-molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN) ACS Chem. Biol. 2006 1 780 790 10.1021/cb600352f 17240976 19 Alimonti A. Nardella C. Chen Z.B. Clohessy J.G. Carracedo A. Trotman L.C...

... 2007 adipocyte differentiation cancer glucose homoeostasis mouse model phosphatase and tensin homologue deleted on chromosome 10 (PTEN) protein kinase B (PKB) The serine/threonine kinase PKB (protein kinase B, also called Akt) constitutes an important node in diverse signalling...

... expression [ 2 ]. 1 email e.rosivatz@ic.ac.uk 7 11 2006 © 2007 The Biochemical Society 2007 diabetes insulin signalling phosphatase and tensin homologue deleted on chromosome 10 (PTEN) phosphatidylinositol 3,4,5-trisphosphate phosphoinositide 3-kinase (PI3K) vanadate...

...@dundee.ac.uk ). 20 10 2006 © 2007 The Biochemical Society 2007 lipid signal phosphatase and tensin homologue deleted on chromosome 10 (PTEN) phosphatidylinositol trisphosphate metabolism phosphorylation reactive oxygen species Src homology 2-containing inositol phosphatase-2 (SHIP2...

... (email suzuki@med.akita-u.ac.jp ). 28 11 2006 © 2007 The Biochemical Society 2007 cardiovasculogenesis endothelial cell p85α phosphatase and tensin homologue deleted on chromosome 10 (PTEN) phosphoinositide-3-kinase (PI3K) tumour angiogenesis PTEN (phosphatase...

... and tensin homologue deleted on chromosome 10 (PTEN) Little is currently known regarding the mechanism of action of mammalian PTEN in the regulation of cell migration. Data using PTEN mutants lacking the C-terminal PDZ-binding site indicates that binding through a (currently unidentified) PDZ...