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Keywords: polyglutamine
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Biochem Soc Trans (2002) 30 (4): 548–551.
Published: 01 August 2002
...L. Masino; A. Pastore A growing number of neurodegenerative diseases are caused by expansion of CAG trinucleotide repeats coding for polyglutamine. The presence of intranuclear inclusions in the affected neuronal cells has suggested a mechanism for pathogenesis based on protein misfolding and...