..., limited processivity RNA polymerase, termed primase, that synthesizes a short oligoribonucleotide primer which is then extended by a DNA polymerase. Thus, primases can initiate synthesis, proceed with primer elongation for a short distance then transfer the primer to a DNA polymerase. Despite these well...

... of oxidative and photolesions. In addition, PrimPol also functions as a primase, catalysing the preferential formation of DNA primers in a zinc finger-dependent manner. Although PrimPol's catalytic activities have been uncovered in vitro , we still know little about how and why it is targeted...

...Georg Lipps The replication protein of the archaeal plasmid pRN1 is a multifunctional enzyme which appears to carry out several steps at the plasmid replication initiation. We recently determined the structure of the minimal primase domain of the replication protein and found out that the primase...

... have been Key words: DNA polymerase, orf904, plasmid family pRN, primase, Sulfolobus. 1e-mail [email protected] determined (Table 1). The most remarkable feature of these elements is the high number of proteins that are not related to proteins in the data banks and thus cannot be annotated...