... ]. Finally, NTL14 (ANAC089) is an ER membrane-bound TF that in ER stress is activated and translocates to the nucleus to up-regulate programmed cell-death related genes; however the activation mechanisms are currently unknown [ 10 ]. These examples highlight that RIP is critical to ER stress responses...

...Ayesha Zahid; Hazrat Ismail; Tengchuan Jin Pyroptosis is a highly inflammatory and lytic type of programmed cell death (PCD) commenced by inflammasomes, which sense perturbations in the cytosolic environment. Recently, several ground-breaking studies have linked a family of pore-forming proteins...

...Birthe Fahrenkrog The baker's yeast, Saccharomyces cerevisiae , is also capable of undergoing programmed cell death or apoptosis, for example in response to viral infection as well as during chronological and replicative aging. Intrinsically, programmed cell death in yeast can be induced...

..., initiating a Ca 2+ -dependent signalling network. SI triggers several downstream events, including depolymerization of the cytoskeleton, phosphorylation of two soluble inorganic pyrophosphatases and an MAPK (mitogen-activated protein kinase). This culminates in PCD (programmed cell death) involving several...

...Patricia Boya; María Angeles Mellén; Enrique J. de la Rosa Programmed cell death, together with proliferation and differentiation, is an essential process during the development of the nervous system. During neurogenesis, neurons and glia are generated in large numbers and, subsequently, they die...

... programmed cell death is prominent. 1 To whom correspondence should be addressed (email [email protected] ). 19 7 2006 © 2006 The Biochemical Society 2006 apoptosis inducing factor (AIF) Bid caspase cytochrome c mitochondrion programmed cell death...

..., it is clear that, as in yeast, actin stabilization can induce cell death and this is mediated through changes involving mitochondria. actin aging apoptosis mitochondrion programmed cell death senescence The yeast actin cytoskeleton is an essential structure that is organized into two major...