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1-9 of 9
Keywords: proliferation
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2025) 53 (01): 181–191.
Published: 06 February 2025
...Claudia Carlantoni; Leon M.H. Liekfeld; Manu Beerens; Maike Frye Endothelial cells (ECs) migrate, sprout, and proliferate in response to (lymph)angiogenic mitogens, such as vascular endothelial growth factors. When ECs reach high confluency and encounter spatial confinement, they establish mature...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (4): 1921–1926.
Published: 13 August 2024
... agreement with JISC. differentiation division patterns division-independent differentiation hypertrophy muscle stem cells proliferation Open access for this article was enabled by the participation of University of Kent in an all-inclusive Read & Publish agreement with Portland...
Articles
Deciphering the role of TRIB1 in regulatory T-cells
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (5): 1075–1078.
Published: 09 October 2015
... by inhibiting their proliferative capacity. Similar observations have been made recently where T-cell receptor (TCR) signalling was described as essential for the homoeostatic proliferation of Tregs in mice and induction of tolerance [ 30 ]. Consequently, proliferative capacities of Tregs are important...
Articles
MKP-2: out of the DUSP-bin and back into the limelight
Available to PurchaseAhmed Lawan, Emma Torrance, Sameer Al-Harthi, Muhannad Shweash, Sulaiman Alnasser, Thikryat Neamatallah, Juliane Schroeder, Robin Plevin
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 235–239.
Published: 19 January 2012
... kinase phosphatase-2 (MKP-2) in proliferation and cell survival J. Biol. Chem. 2011 286 12933 12943 52 Rahmouni S. Cerignoli F. Alonso A. Tsutji T. Henkens R. Zhu C. Louis-dit-Sully C. Moutschen M. Jiang W. Mustelin T. Loss of the VHR dual-specific...
Articles
Controlling embryonic stem cell proliferation and pluripotency: the role of PI3K- and GSK-3-dependent signalling
Available to PurchaseMelanie J. Welham, Emmajayne Kingham, Yolanda Sanchez-Ripoll, Benjamin Kumpfmueller, Michael Storm, Heather Bone
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (2): 674–678.
Published: 22 March 2011
... pluripotency, proliferation and differentiation (i.e. cell fate) need to be understood so that pluripotency can be maintained during expansion, while differentiation to specific lineages can be induced accurately when required. The present review focuses on the potential roles that PI3K (phosphoinositide 3...
Articles
The tuberous sclerosis complex: balancing proliferation and survival
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (2): 466–471.
Published: 22 March 2011
..., proliferation and survival. In the present paper, we review recent evidence highlighting the notion that the TSC1/2 complex simultaneously controls mTOR-dependent and mTOR-independent signals critical for the balancing of cell proliferation and cell death. 1 To whom correspondence should be addressed...
Articles
Mouse models for BRAF -induced cancers
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (5): 1329–1333.
Published: 25 October 2007
... kinase) kinase] and ERK phosphorylation leading to an increase in cell proliferation, cell survival, transformation, tumorigenicity, invasion and vascular development. Many of these hallmarks of cancer can be reversed by treatment of cells with siRNA (small interfering RNA) to BRAF or by inhibiting MEK...
Articles
Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (4): 694–697.
Published: 01 August 2005
... the normal maintenance of this tissue: differentiation, migration, proliferation and apoptosis. Indeed, APC is involved in the regulation of β-catenin and it also is an important regulator of the cytoskeleton. Thus mutations in APC lead to the accumulation of β-catenin, which causes changes...
Articles
Receptor tyrosine kinase–GPCR signal complexes
Available to Purchase
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2003) 31 (6): 1220–1225.
Published: 01 December 2003
... differentiation growth factor receptor lysophosphatidic acid p42/p44 mitogen-activated protein kinase proliferation sphingosine 1-phosphate (S1P) Abbreviations used: ASM, airway smooth muscle; GPCR, G-protein-coupled receptor; GRK2, G-protein-coupled receptor kinase 2; IGF-1, insulin-like growth...