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Keywords: prospermatogonia
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Biochem Soc Trans (2022) 50 (6): 1875–1884.
Published: 01 December 2022
... is a prerequisite for de novo DNA methylation. When ZBTB43 changes DNA structure from the left-handed zigzag shaped Z-DNA to the regular smooth right-handed B-DNA, it also generates a suitable substrate for the de novo DNA methyltransferase, DNMT3A. By instructing de novo DNA methylation at PPRs in prospermatogonia...