... under a transformative agreement with JISC. cartilage metalloproteases osteoarthritis protease inhibitor serine proteases serpin This clade also only contains one member — SerpinD1 (also known as Heparin Cofactor II) which is rapid inhibitor of thrombin, but like SerpinC1, only...

... activation system is tightly regulated by host serine protease inhibitors: Plg activator inhibitors 1 and 2 (PAI-1 and PAI-2). ( D ) Active Plm released from targets will be immediately removed from the circulation by the specific inhibitor α 2 -antiplasmin or the housekeeping α 2 -macroglobulin (see text...

... disorders of the lungs. Two unglycosylated natural protease inhibitors, SLPI (secretory leucocyte protease inhibitor) and elafin, and its precursor trappin-2 that are found in the lungs, have therapeutic potential for reducing the protease-induced inflammatory response. This review examines the multifaceted...

...Katalin Kondás; György Szláma; Alinda Nagy; Mária Trexler; László Patthy WFIKKN1 and WFIKKN2 are two closely related multidomain proteins consisting of a WAP (whey acidic protein)-, a follistatin-, an immunoglobulin-, two Kunitz-type protease inhibitor-domains and an NTR domain (netrin domain...

... or cancer. The completion of the human genome sequence allowed us to determine that more than 2% of all human genes are proteases or protease inhibitors, reflecting the importance of proteolysis in human biology. To understand better the complexity of proteases in human and other model organisms, we have...