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Keywords: protein acyltransferase
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Biochem Soc Trans (2017) 45 (4): 923–928.
Published: 16 June 2017
... with palmitate and is the site of the acyl–enzyme intermediate [ 25 ]. DHHC proteins are protein acyltransferases (PATs) that catalyze the addition of palmitate onto substrate proteins [ 7 , 8 ]. Conserved throughout eukaryotes, families of DHHC proteins range in size from five members...
Biochem Soc Trans (2013) 41 (1): 29–34.
Published: 29 January 2013
.... Palmitoylation regulates protein membrane interactions, activity, trafficking and stability and can be constitutive or regulated by signalling inputs. A family of PATs (protein acyltransferases) is responsible for modifying proteins with palmitate or other long-chain fatty acids on the cytoplasmic face...