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Keywords: protein kinase B (PKB)
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Articles

mTORC1 regulates CD8 + T-cell glucose metabolism and function independently of PI3K and PKB

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David K. Finlay
Journal: Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (2): 681–686.
https://doi.org/10.1042/BST20120359
Published: 21 March 2013
... [email protected] 19 12 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 cytotoxic T-lymphocyte glycolysis hypoxia-inducible factor 1α (HIF1α) mammalian target of rapamycin complex 1 (mTORC1) protein kinase B (PKB) trafficking mTOR (mammalian target...
View articletitled, mTORC1 regulates CD8 + T-cell glucose metabolism and function independently of PI3K and PKB
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Articles

Protein kinases, from B to C

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A.J. Cameron, M. De Rycker, V. Calleja, D. Alcor, S. Kjaer, B. Kostelecky, A. Saurin, A. Faisal, M. Laguerre, B.A. Hemmings, N. McDonald, B. Larijani, P.J. Parker
Journal: Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (5): 1013–1017.
https://doi.org/10.1042/BST0351013
Published: 25 October 2007
... ). 1 7 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 protein kinase B (PKB) protein kinase C (PKC) phosphoinositide-dependent kinase 1 (PDK1) phosphorylation pleckstrin homology domain (PH domain) protein serine/threonine kinase In mammals, cellular...
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Articles

Exercise- and nutrient-controlled mechanisms involved in maintenance of the musculoskeletal mass

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M.J. Rennie
Journal: Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (5): 1302–1305.
https://doi.org/10.1042/BST0351302
Published: 25 October 2007
... kinase B (PKB) protein turnover The machinery of the body, i.e. muscle, tendon, ligament and bone, accounts for the overwhelming amount of protein-bound amino acid in the body, with the collagen in connective tissue alone accounting for approx. 3 kg of body weight. We now have a much better idea...
View articletitled, Exercise- and nutrient-controlled mechanisms involved in maintenance of the musculoskeletal mass
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Articles

Regulation of class IA PI3Ks: is there a role for monomeric PI3K subunits?

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B. Geering, P.R. Cutillas, B. Vanhaesebroeck
Journal: Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (2): 199–203.
https://doi.org/10.1042/BST0350199
Published: 20 March 2007
...) phosphorylation protein kinase B (PKB) Class I PI3Ks (phosphoinositide 3-kinases) generate PIP 3 (phosphatidylinositol 3,4,5-trisphosphate), which interacts with specialized lipid-binding domains present in protein kinases [such as Akt/PKB (protein kinase B)], regulators of small GTPases and scaffolding...
View articletitled, Regulation of class IA PI3Ks: is there a role for monomeric PI3K subunits?
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Articles

Physiological roles of PKB/Akt isoforms in development and disease

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B. Dummler, B.A. Hemmings
Journal: Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (2): 231–235.
https://doi.org/10.1042/BST0350231
Published: 20 March 2007
... [email protected] ). 16 12 2006 © 2007 The Biochemical Society 2007 adipocyte differentiation cancer glucose homoeostasis mouse model phosphatase and tensin homologue deleted on chromosome 10 (PTEN) protein kinase B (PKB) The serine/threonine kinase PKB (protein kinase B, also...
View articletitled, Physiological roles of PKB/Akt isoforms in development and disease
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Articles

Regulation of small GTP-binding proteins by insulin

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G.I. Welsh, I. Hers, M. Wherlock, J.M. Tavaré
Journal: Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (2): 209–212.
https://doi.org/10.1042/BST0340209
Published: 20 March 2006
... in the activation of the target Rab(s) that is necessary for the translocation step. 21 11 2005 © 2006 The Biochemical Society 2006 AS160 glucose homoeostasis GTPase insulin protein kinase B (PKB) Rab Insulin is the primary hormone that is responsible for the control of glucose...
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Articles

BCR activation of PI3K is Vav-independent in murine B cells

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E. Vigorito, E. Clayton, M. Turner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2004) 32 (5): 781–784.
https://doi.org/10.1042/BST0320781
Published: 26 October 2004
... together with our previous observation that protein kinase B phosphorylation is normal in Vav-deficient B-cells, we suggest that PI3K activation is Vav-independent in response to strong signals delivered by multivalent cross-linking. B-lymphocyte phosphoinositide 3-kinase (PI3K) protein kinase B (PKB...
View articletitled, BCR activation of PI3K is Vav-independent in murine B cells
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