... junctional form of Cx43 and in its hemichannel configuration. We present the current knowledge of protein kinase C (PKC)-dependent regulation of Cx43 and discuss the divergent results. © The Authors Journal compilation © 2015 Biochemical Society 2015 conductance connexin fluorescent dye...

...Aideen Long; Michael Freeley Protein kinase C (PKC) is a family of ten serine/threonine kinases that have diverse roles in the signalling pathways regulating cellular proliferation, differentiation, apoptosis and immune responses. Elucidating roles for individual PKC isoforms in the immune...

...Alessandro Poli; Sara Mongiorgi; Lucio Cocco; Matilde Y. Follo Protein kinases C (PKCs) are a family of serine/threonine kinases which act as key regulators in cell cycle progression and differentiation. Studies of the involvement of PKCs in cell proliferation showed that their role is dependent...

... signalling Golgi Ras plasma membrane (PM) protein kinase C 1 email [email protected] 8 3 2005 © 2005 The Biochemical Society 2005 In summary, we have shown that the PM is not unique as a platform from which Ras proteins regulate signalling pathways. The cytoplasmic...

... muscle and damage to the endothelial cell by a similar mechanism. (ii) Key pathogenetic events in this mechanism very likely include increased fatty acid esterification, protein kinase C activation, an increase in oxidative stress (demonstrated to date in endothelium) and alterations in the inhibitor κB...

... or that have key roles in the regulation of the fusion machinery are now well established [l]. Their functional importance in the overall process of exocytosis has been extensively demonstrated in molecular genetic studies in many organisms [2,3]. Key words: Csp, Munc 18, Noc2, protein kinase C, Rab3, SNARE...

... interacting with C-kinase PKC, protein kinase C The Interface of Receptor Signalling and Trafficking Proteins involved in the synaptic organization of AMPA (a-amino-3-hydroxy-5- methylisoxazolepropionate) receptors J. Henley' MRC Centre for Synaptic Plasticity, Anatomy Department, School of Medical...

... solution Ins(1,4,5)P 3 ;inositol 1,4,5 trisphosphate L-NAME N G Nitro - L - arginine methylester TCA trichloroacetic acid TPA phorbol-12 myristate-13 acetate PKC protein kinase C 654th Meeting Leicester: 654th Meeting Held at the University of Leicester 4–7 April, 1995 Biochemical...