... with similar properties will no doubt guide the development of new approaches to the design of water soluble membrane proteins. membrane proteins protein engineering protein stability protein structure Integral membrane proteins (IMPs) exist within lipid membranes. Current estimates suggest...

... is the statistical weight of the interaction between the R and F region, Φ int =exp (−Δ g int / RT ). © The Authors Journal compilation © 2012 Biochemical Society 2012 allostery conformational fluctuation ensemble glucocorticoid receptor intrinsic disorder protein stability Allostery...

... binding protein dynamics protein stability sodium/calcium exchanger (NCX) The NCX (Na + /Ca 2+ exchanger) is a crucial membrane protein controlling cytosolic Ca 2+ levels. In cardiomyocytes and neurons, NCX is the main extrusion mechanism across the plasma membrane [ 1 , 2 ]. Four NCX genes...

...M.M. Gromiha Prediction of protein stability upon amino acid substitution is a challenging problem and it will be helpful for designing stable mutants. We have developed a thermodynamic database for proteins and mutants (ProTherm), which has more than 20000 thermodynamic data along with sequence...

... The Authors Journal compilation © 2007 Biochemical Society 2007 Bacillus subtilis laccase CotA laccase fluorescence multicopper oxidase protein stability redox potential Laccases are members of the multicopper oxidase family of enzymes that includes ascorbate oxidase and ceruloplasmin [ 1...

... compilation © 2007 Biochemical Society 2007 catalytic scavenger functional state human phosphate-binding protein paraoxonase protein stability purification HDL offers a hydrophobic harbour for PON1 after the secretion by liver and provides a stabilizing environment for PON1 function(s) [ 13...

...L. Ye; Z. Wu; M. Eleftheriou; R. Zhou Recent NMR experiments have revealed that a single residue mutation W62G on protein hen's-egg white lysozyme can cause a dramatic loss of long-range interactions and protein stability; however, the molecular mechanism for this surprising phenomenon...