... Society 2019 phosphorylation/dephosphorylation protein turnover protein–protein interactions ubiquitin signalling ubiquitins The study of ubiquitin has continued at pace since its identification over 40 years ago [ 1 ]. However, whilst knowledge of covalent ubiquitin conjugation...

... disordered proteins protein turnover RNA localization Understanding how proteins, which are polymers of amino acids, carry out different functions in a cell has been a problem of considerable interest. In a series of elegant publications, Christian Anfinsen and colleagues proposed that the sequence...

...M.J. Rennie The mechanisms of maintenance of the protein mass of muscle and associated connective tissue and bone are becoming more accessible as a result of the use of a combination of well-established techniques for measurement of protein turnover and measurement of protein expression...

... that a tumour suppressor candidate protein binds to extreme C-terminal region of PTEN and regulates PTEN protein turnover. 1 To whom correspondence should be addressed (e-mail tmaehama@rinshoken.or.jp ). PI-3 Kinase in Signalling and Disease, a Biochemical Society Focused Meeting held at Novartis...