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Keywords: pulmonary arterial hypertension
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2024) 52 (3): 1515–1528.
Published: 08 May 2024
...Wei Li; Kate Quigley Pulmonary arterial hypertension (PAH) is a rare and life-threatening vascular disorder, characterised by abnormal remodelling of the pulmonary vessels and elevated pulmonary artery pressure, leading to right ventricular hypertrophy and right-sided heart failure. The importance...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2019) 47 (3): 779–791.
Published: 24 May 2019
... and BMP10 bind preferentially to the high-affinity type I receptor activin receptor-like kinase 1 on vascular endothelial cells. Recently, many reports have highlighted the important roles of BMP9 in cardiovascular disease, particularly pulmonary arterial hypertension. In vivo , BMP9 activity...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (3): 524–529.
Published: 01 June 2015
...Yvonne Dempsie; Patricia Martin; Paul D. Upton Pulmonary arterial hypertension (PAH) is a complex, multi-factorial disorder characterized by both constriction and remodelling of the distal pulmonary vasculature. This leads to increased pulmonary pressures and eventually right heart failure. Current...