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Keywords: quantum mechanical tunnelling
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Biochem Soc Trans (2009) 37 (2): 349–353.
Published: 20 March 2009
... and substrate in a reactive configuration from which hydride is transferred by quantum mechanical tunnelling. In the present paper, we review results from experiments that probe the influence of protein dynamics on the chemical step of the reaction catalysed by TmDHFR (DHFR from Thermotoga maritima...