.... Nutrient sensing via neurons that express TAX-2/4 (α and β subunits of cGMP-gated channel) is necessary for worms to undergo quiescence as the loss of egl4, which encodes a protein kinase downstream of cGMP signaling hampers quiescence [ 59 ]. While nutrient deprivation can induce diapause, most organisms...

[email protected] ). 11 4 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 differentiation quiescence rapamycin target of rapamycin complex 4 (TORC4) trypanosome Since its discovery in 1991 [ 1 ], TOR (target of rapamycin) has emerged as a multi-tasking kinase...

... translational efficiency when cell growth is arrested, a physiologically relevant state occurring during inflammation, angiogenesis and monocyte differentiation. Under these conditions, called quiescence, the miRNP (microribonucleoprotein)-associated proteins FXR1 (Fragile X mental retardation-related protein 1...

... in CML. 1 To whom correspondence should be addressed (email [email protected] ). 8 6 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 BCR-ABL farnesyl transferase myeloid leukaemia quiescence stem cell tyrosine kinase IM-insensitivity...