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Keyword: reactive oxygen species (ROS)
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Articles
Biochem Soc Trans (2016) 44 (4): 1111-1116.
Published: 15 August 2016
... Biochemical Society 2016 cancer metabolism fumarate hydratase hypoxia isocitrate dehydrogenase reactive oxygen species (ROS) succinate dehydrogenase Metabolic reprogramming is now a recognized hallmark of cancer transformation. The first observation of this phenotype was in the early 1920s...
Articles
Biochem Soc Trans (2015) 43 (4): 680-686.
Published: 03 August 2015
... (email dzhang@pharmacy.arizona.edu ) . 9 2 2015 © 2015 Authors; published by Portland Press Limited 2015 chemoprevention/chemoresistance Hrd1 Kelch-like ECH-associated protein 1 (Keap1) nuclear factor erytheroid-derived-2-like 2 (Nrf2) reactive oxygen species (ROS) ubiquitin...
Articles
Biochem Soc Trans (2014) 42 (4): 922-927.
Published: 11 August 2014
... important for lifespan and immune function. 1 To whom correspondence should be addressed (email h.r.griffiths@aston.ac.uk ). 2 6 2014 © The Authors Journal compilation © 2014 Biochemical Society 2014 ageing oxidation reactive oxygen species (ROS) rheumatoid arthritis thiol...
Articles
Biochem Soc Trans (2014) 42 (4): 934-938.
Published: 11 August 2014
... To whom correspondence should be addressed (email t.cotter@ucc.ie ). 31 3 2014 © The Authors Journal compilation © 2014 Biochemical Society 2014 cancer hydrogen peroxide (H 2 O 2 ) NADPH oxidase (Nox) reactive oxygen species (ROS) signalling Generation of ROS (reactive...
Articles
Biochem Soc Trans (2014) 42 (4): 959-964.
Published: 11 August 2014
... oxygen species (ROS) redox imaging RTT (Rett syndrome) was initially described in 1966 as an “unusual brain atrophy syndrome” [ 1 , 2 ]. It primarily affects girls with a prevalence of 1:10000–15000, and is associated with severe cognitive impairment. Typically, RTT progresses in four stages...
Articles
Biochem Soc Trans (2014) 42 (2): 370-376.
Published: 20 March 2014
... death (PCD) reactive oxygen species (ROS) self-incompatibility Successful sexual reproduction in many flowering plants involves a genetically controlled mechanism called SI (self-incompatibility). SI is genetically controlled by a multi-allelic S -locus that encodes linked pollen and pistil...
Articles
Biochem Soc Trans (2014) 42 (1): 1-10.
Published: 23 January 2014
... addressed (email areddy@cantab.net ). 14 10 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 circadian rhythm peroxiredoxin reactive oxygen species (ROS) redox homoeostasis Circadian rhythms are arguably one of life's most basic mechanisms, regulating the...
Articles
Biochem Soc Trans (2012) 40 (4): 735-738.
Published: 20 July 2012
... cleavage Creutzfeldt–Jakob disease octapeptide repeat prion processing reactive oxygen species (ROS) As for numerous proteins, the endogenous PrP C (normal cellular prion protein) undergoes a number of post-translational cleavage events during its life. The main cleavage processes are so...
Articles
Biochem Soc Trans (2012) 40 (1): 129-132.
Published: 19 January 2012
... compilation © 2012 Biochemical Society 2012 atherosclerosis cancer embryonic development reactive oxygen species (ROS) Podosomes and invadopodia can be defined as dynamic actin-rich protrusions of the ventral membrane of certain cell types [ 1 ]. They are the sites of attachment to, and...
Articles
Biochem Soc Trans (2011) 39 (6): 1715-1718.
Published: 21 November 2011
... Society 2011 DNA damage response Hutchinson–Gilford progeria syndrome (HGPS) lamin laminopathy progeria reactive oxygen species (ROS) The progeroid laminopathies include HGPS (Hutchinson–Gilford progeria syndrome), atypical Werner's syndrome, MAD (mandibuloacral dysplasia) and RD...
Articles
Biochem Soc Trans (2011) 39 (6): 1683-1686.
Published: 21 November 2011
... organization Emery–Dreifuss muscular dystrophy (EDMD) Hutchinson–Gilford progeria syndrome (HGPS) induced pluripotent stem cell (iPSC) nuclear envelope disease reactive oxygen species (ROS) The Nuclear Envelope Disease and Chromatin Organization UK was formed in 2005, to unite and promote...
Articles
Biochem Soc Trans (2011) 39 (5): 1288-1292.
Published: 21 September 2011
... 6 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 electrochemical detection isolated mitochondrion macrophage optical nanosensor reactive oxygen species (ROS) superoxide dismutase (SOD) ROS (reactive oxygen species) such as superoxide (O 2 – ) play a...
Articles
Biochem Soc Trans (2011) 39 (5): 1221-1225.
Published: 21 September 2011
... dichlorodihydrofluorescein or dihydrorhodamine. 1 email balarama@mcw.edu . 15 7 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 cell signalling fluorescence mitochondrion reactive nitrogen species (RNS) reactive oxygen species (ROS) redox biology superoxide...
Articles
Biochem Soc Trans (2011) 39 (5): 1305-1309.
Published: 21 September 2011
... correspondence should be addressed (email irina.shabalina@wgi.su.se ). 15 6 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 carbonyl cyanide p -trifluoromethoxyphenylhydrazone (FCCP) membrane potential mitochondrion oxidative stress reactive oxygen species (ROS...
Articles
Biochem Soc Trans (2011) 39 (5): 1471-1475.
Published: 21 September 2011
... signalling quorum sensing reactive oxygen species (ROS) stress defence and dying yeast colony architecture and differentiation Most knowledge of yeast cell reproduction, aging and dying comes from laboratory investigations, where cells are often treated in liquid cultures grown under various...
Articles
Biochem Soc Trans (2011) 39 (5): 1226-1232.
Published: 21 September 2011
... 7 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 advanced glycation end-product (AGE) reactive nitrogen species (RNS) reactive oxygen species (ROS) reactive sulfur species (RSS) rheumatoid arthritis (RA) RA (rheumatoid arthritis) is an inflammatory...
Articles
Biochem Soc Trans (2011) 39 (5): 1273-1278.
Published: 21 September 2011
... inflammation reactive oxygen species (ROS) redox signalling regulatory T-cell (T reg cell) The principal function of the immune system is to discriminate between self and non-self, and the effector T-cell arm (including TH1, TH2 and TH17; see Figure 1 ) is responsible, along with the B-cell arm of...
Articles
Biochem Soc Trans (2011) 39 (5): 1538-1543.
Published: 21 September 2011
... Society 2011 cytochrome c mitochondrion programmed cell death (PCD) reactive oxygen species (ROS) Saccharomyces cerevisiae YCA1 The term PCD (programmed cell death) describes a highly heterogeneous process regulated by distinct but sometimes overlapping pathways including apoptosis...
Articles
Biochem Soc Trans (2011) 39 (5): 1544-1548.
Published: 21 September 2011
... Aspergillus nidulans cell death endoplasmic reticulum farnesol reactive oxygen species (ROS) FOH (farnesol), a non-sterol isoprenoid produced by dephosphorylation of farnesyl pyrophosphate, has been shown to inhibit proliferation and induce apoptosis in neoplastic cell lines and also to be...
Articles
Biochem Soc Trans (2008) 36 (5): 976-980.
Published: 19 September 2008
... complex I mitochondrion NADH:ubiquinone oxidoreductase oxidative stress reactive oxygen species (ROS) reverse electron transport The electron transport chain in mitochondria is a significant source of cellular ROS. Historically, respiratory complexes I and III have been considered two major...
Articles
Biochem Soc Trans (2008) 36 (5): 930-934.
Published: 19 September 2008
... ). 8 5 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 diabetes lipotoxicity mitochondrial DNA (mtDNA) oxidative stress pancreatic β-cell reactive oxygen species (ROS) Pancreatic β-cells are poised to sense glucose and other nutrient secretagogues to...
Articles
Biochem Soc Trans (2007) 35 (1): 28-32.
Published: 22 January 2007
... metabolism protein phosphorylation photosynthesis reactive oxygen species (ROS) sucrose phosphate synthase (SPS) This review focuses on phosphorylation and signalling in plants. It takes quite a broad overview of the subject, but, within that, highlights topics that are current research interests...
Articles
Biochem Soc Trans (2005) 33 (6): 1385-1389.
Published: 26 October 2005
...) lysophosphatidylcholine mitochondrion oxidized lipid reactive oxygen species (ROS) thiol The formation of low molecular mass second messengers as cell-signalling molecules is well established in the redox cell-signalling field. The molecules involved in signalling are structurally diverse and include the ROS...
Articles
Biochem Soc Trans (2005) 33 (6): 1394-1396.
Published: 26 October 2005
...) reactive oxygen species (ROS) superoxide production NO is an important regulator of cell viability and death depending on its concentration, source of production and pathological conditions. In a variety of cell types, expression of iNOS (inducible nitric oxide synthase) can be induced by...
Articles
Biochem Soc Trans (2005) 33 (5): 1123-1125.
Published: 26 October 2005
... prion protein (PrP) proteolysis reactive oxygen species (ROS) Prion diseases occur when a conformational conversion in the normal PrP C [cellular isoform of PrP (prion protein)] produces a proteinase-resistant form PrP Sc (scrapie isoform of PrP). Examples of such neurodegenerative disorders...
Articles
Biochem Soc Trans (2005) 33 (2): 375-379.
Published: 01 April 2005
... © 2005 The Biochemical Society 2005 abiotic stress abscisic acid (ABA) osmoregulation reactive oxygen species (ROS) upstream sensing upstream signalling Abiotic stress can limit crop productivity and is a key determinant of the natural distribution of plant species. Abiotic stresses, such...
Articles
Biochem Soc Trans (2004) 32 (6): 1018-1020.
Published: 26 October 2004
... 2004 hydrogen peroxide phosphatase protein tyrosine phosphatase (PTP) reactive oxygen species (ROS) redox signalling superoxide Regulated reversible phosphorylation of proteins and other cellular molecules plays a ubiquitous role in the control of cellular behaviour. Several different...
Articles
Biochem Soc Trans (2004) 32 (6): 1070-1071.
Published: 26 October 2004
... The Biochemical Society 2004 elimination of mitochondria fission fusion mitochondrial inhibitors reactive oxygen species (ROS) Mitochondria in various cell types form a dynamic reticulum [ 1 ], which was suggested to play the role of a cable-like energy transporting system in the cell...
Articles
Biochem Soc Trans (2003) 31 (6): 1441-1444.
Published: 01 December 2003
... the Biochemical Society held at the University of Essex, Colchester, 2–4 July 2003 9 July 2003 © 2003 Biochemical Society 2003 apoptosis growth factor Mn superoxide dismutase Ras reactive oxygen species (ROS) senescence Abbreviations used: AP-1, activator protein-1...