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1-29 of 29
Keywords: reactive oxygen species (ROS)
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Articles
Isocitrate dehydrogenase (IDH), succinate dehydrogenase (SDH), fumarate hydratase (FH): three players for one phenotype in cancer?
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2016) 44 (4): 1111–1116.
Published: 15 August 2016
... Society 2016 cancer metabolism fumarate hydratase hypoxia isocitrate dehydrogenase reactive oxygen species (ROS) succinate dehydrogenase Dysfunction in IDH, SDH and FH are also involved, directly or indirectly, with the higher levels of ROS often found in cancer cells. Because...
Articles
Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention
Available to PurchaseBryan Harder, Tao Jiang, Tongde Wu, Shasha Tao, Montserrat Rojo de la Vega, Wang Tian, Eli Chapman, Donna D. Zhang
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (4): 680–686.
Published: 03 August 2015
... (email [email protected] ) . 9 2 2015 © 2015 Authors; published by Portland Press Limited 2015 chemoprevention/chemoresistance Hrd1 Kelch-like ECH-associated protein 1 (Keap1) nuclear factor erytheroid-derived-2-like 2 (Nrf2) reactive oxygen species (ROS) ubiquitin...
Articles
Aberrant redox homoeostasis and mitochondrial dysfunction in Rett syndrome
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (4): 959–964.
Published: 11 August 2014
... by us in the hippocampus of symptomatic Mecp2 − /y mice [ 24 ], clearly indicate that in RTT the brain also experiences oxidative stress. antioxidant autism spectrum disorder mitochondrial disease oxidative stress reactive oxygen species (ROS) redox imaging RTT (Rett syndrome...
Articles
Thioredoxin as a putative biomarker and candidate target in age-related immune decline
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (4): 922–927.
Published: 11 August 2014
... with the plasma membrane; it is trafficked with a limited number of cytosolic proteins via the leaderless secretory pathway, with anchorage in the membrane probably mediated by palmitoylation of cysteine as described for plant cell Trx-1 [ 18 ]. ageing oxidation reactive oxygen species (ROS) rheumatoid...
Articles
ROS signalling, NADPH oxidases and cancer
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (4): 934–938.
Published: 11 August 2014
... correspondence should be addressed (email [email protected] ). 31 3 2014 © The Authors Journal compilation © 2014 Biochemical Society 2014 cancer hydrogen peroxide (H 2 O 2 ) NADPH oxidase (Nox) reactive oxygen species (ROS) signalling Generation of ROS (reactive oxygen species) has...
Articles
Self-incompatibility in Papaver : advances in integrating the signalling network
Available to PurchaseDeborah J. Eaves, Carlos Flores-Ortiz, Tamanna Haque, Zongcheng Lin, Nianjun Teng, Vernonica E. Franklin-Tong
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (2): 370–376.
Published: 20 March 2014
... death (PCD) reactive oxygen species (ROS) self-incompatibility Successful sexual reproduction in many flowering plants involves a genetically controlled mechanism called SI (self-incompatibility). SI is genetically controlled by a multi-allelic S -locus that encodes linked pollen and pistil...
Articles
Rethinking the clockwork: redox cycles and non-transcriptional control of circadian rhythms
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (1): 1–10.
Published: 23 January 2014
... oxygen species (ROS) redox homoeostasis Circadian rhythms are arguably one of life's most basic mechanisms, regulating the timekeeping of a large swath of biological processes at the molecular, metabolic and behavioural level. It is widely believed that the evolution of these rhythms offers key...
Articles
Prion processing: a double-edged sword?
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (4): 735–738.
Published: 20 July 2012
... cleavage Creutzfeldt–Jakob disease octapeptide repeat prion processing reactive oxygen species (ROS) ADAM a disintegrin and metalloproteinase CDP chronic demyelinating polyneuropathy CJD Creutzfeldt–Jakob disease OR octapeptide repeat PrP prion protein PrP C...
Articles
Cell migration and invasion in human disease: the Tks adaptor proteins
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 129–132.
Published: 19 January 2012
... Wiskott–Aldrich syndrome protein. atherosclerosis cancer embryonic development reactive oxygen species (ROS) Podosomes and invadopodia can be defined as dynamic actin-rich protrusions of the ventral membrane of certain cell types [ 1 ]. They are the sites of attachment...
Articles
The role of DNA damage in laminopathy progeroid syndromes
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (6): 1715–1718.
Published: 21 November 2011
... email [email protected] 5 8 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 DNA damage response Hutchinson–Gilford progeria syndrome (HGPS) lamin laminopathy progeria reactive oxygen species (ROS) The progeroid laminopathies include HGPS...
Articles
Nuclear Envelope Disease and Chromatin Organization
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (6): 1683–1686.
Published: 21 November 2011
... © The Authors Journal compilation © 2011 Biochemical Society 2011 chromatin organization Emery–Dreifuss muscular dystrophy (EDMD) Hutchinson–Gilford progeria syndrome (HGPS) induced pluripotent stem cell (iPSC) nuclear envelope disease reactive oxygen species (ROS) The Nuclear...
Articles
Electrochemical and optical sensing of reactive oxygen species: pathway to an integrated intracellular and extracellular measurement platform
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (5): 1288–1292.
Published: 21 September 2011
... released by endothelial cells using different NO-sensing chemistries Anal. Bioanal. Chem. 2004 378 1594 1600 © The Authors Journal compilation © 2011 Biochemical Society 2011 electrochemical detection isolated mitochondrion macrophage optical nanosensor reactive oxygen species (ROS...
Articles
Oxidative chemistry of fluorescent dyes: implications in the detection of reactive oxygen and nitrogen species
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (5): 1221–1225.
Published: 21 September 2011
... dichlorodihydrofluorescein or dihydrorhodamine. 1 email [email protected] . 15 7 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 cell signalling fluorescence mitochondrion reactive nitrogen species (RNS) reactive oxygen species (ROS) redox biology superoxide...
Articles
Mitochondrial (‘mild’) uncoupling and ROS production: physiologically relevant or not?
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (5): 1305–1309.
Published: 21 September 2011
... correspondence should be addressed (email [email protected] ). 15 6 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 carbonyl cyanide p -trifluoromethoxyphenylhydrazone (FCCP) membrane potential mitochondrion oxidative stress reactive oxygen species (ROS...
Articles
Farnesol-induced cell death in the filamentous fungus Aspergillus nidulans
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (5): 1544–1548.
Published: 21 September 2011
... endoplasmic reticulum farnesol reactive oxygen species (ROS) 8th International Meeting on Yeast Apoptosis: An Independent Meeting held at Keynes College, University of Kent, Canterbury, U.K., 2–6 May 2011. Organized and Edited by Paula Ludovico (University of Minho, Braga, Portugal). AIF...
Articles
Aging and longevity of yeast colony populations: metabolic adaptation and differentiation
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (5): 1471–1475.
Published: 21 September 2011
... signalling quorum sensing reactive oxygen species (ROS) stress defence and dying yeast colony architecture and differentiation Most knowledge of yeast cell reproduction, aging and dying comes from laboratory investigations, where cells are often treated in liquid cultures grown under various...
Articles
Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease
Available to PurchasePaul G. Winyard, Brent Ryan, Paul Eggleton, Ahuva Nissim, Emma Taylor, Maria Letizia Lo Faro, Torsten Burkholz, Katalin E. Szabó-Taylor, Bridget Fox, Nick Viner, Richard C. Haigh, Nigel Benjamin, Andrew M. Jones, Matthew Whiteman
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (5): 1226–1232.
Published: 21 September 2011
... 7 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 advanced glycation end-product (AGE) reactive nitrogen species (RNS) reactive oxygen species (ROS) reactive sulfur species (RSS) rheumatoid arthritis (RA) RA (rheumatoid arthritis) is an inflammatory...
Articles
Free radicals and redox signalling in T-cells during chronic inflammation and ageing
Available to PurchaseHelen R. Griffiths, Christopher R. Dunston, Stuart J. Bennett, Melissa M. Grant, Darren C. Phillips, George D. Kitas
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (5): 1273–1278.
Published: 21 September 2011
... ). 2 Present address: Birmingham Dental School, St Chad's Queensway, Birmingham B4 6NN, U.K. 3 Present address: Abbott Laboratories, Abbott Park, IL 60064, U.S.A. 18 7 2011 ageing glutathione inflammation reactive oxygen species (ROS) redox signalling regulatory T...
Articles
Achievements and perspectives in yeast acetic acid-induced programmed cell death pathways
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (5): 1538–1543.
Published: 21 September 2011
... the altruistic role of some yeast cells to increase the fitness of the whole cell population [ 4 , 5 ]. © The Authors Journal compilation © 2011 Biochemical Society 2011 cytochrome c mitochondrion programmed cell death (PCD) reactive oxygen species (ROS) Saccharomyces cerevisiae YCA1...
Articles
The production of reactive oxygen species by complex I
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (5): 976–980.
Published: 19 September 2008
... oxidoreductase oxidative stress reactive oxygen species (ROS) reverse electron transport Integration of Structures, Spectroscopies and Mechanisms: Second Joint German/British Bioenergetics Conference, a Biochemical Society Focused Meeting held at University of Edinburgh, U.K., 2–4 April 2008...
Articles
The sensitivity of pancreatic β-cells to mitochondrial injuries triggered by lipotoxicity and oxidative stress
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (5): 930–934.
Published: 19 September 2008
... be addressed (email [email protected] ). 8 5 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 diabetes lipotoxicity mitochondrial DNA (mtDNA) oxidative stress pancreatic β-cell reactive oxygen species (ROS) Increased oxidative stress...
Articles
Exploring the role of protein phosphorylation in plants: from signalling to metabolism
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (1): 28–32.
Published: 22 January 2007
.... It is possible that this propensity for methionine residues to oxidize may be exploited in response to signalling by ROS. 1 email [email protected] 31 8 2006 © 2007 The Biochemical Society 2007 nitrate plant metabolism protein phosphorylation photosynthesis reactive oxygen...
Articles
Reactive oxygen species (ROS)-mediated β-cleavage of the prion protein in the mechanism of the cellular response to oxidative stress
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (5): 1123–1125.
Published: 26 October 2005
... prion protein (PrP) proteolysis reactive oxygen species (ROS) Prion diseases occur when a conformational conversion in the normal PrP C [cellular isoform of PrP (prion protein)] produces a proteinase-resistant form PrP Sc (scrapie isoform of PrP). Examples of such neurodegenerative disorders...
Articles
What else has to happen for nitric oxide to induce cell death?
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (6): 1394–1396.
Published: 26 October 2005
... death is promoted by hypoxia and low glycolysis) or (b) by derivative RNS or induced ROS, in which case death depends on overcoming antioxidant defences. © 2005 The Biochemical Society 2005 apoptosis hypoxia necrosis nitric oxide (NO) reactive oxygen species (ROS) superoxide production...
Articles
Cell signalling by oxidized lipids and the role of reactive oxygen species in the endothelium
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (6): 1385–1389.
Published: 26 October 2005
...) lysophosphatidylcholine mitochondrion oxidized lipid reactive oxygen species (ROS) thiol The formation of low molecular mass second messengers as cell-signalling molecules is well established in the redox cell-signalling field. The molecules involved in signalling are structurally diverse and include the ROS...
Articles
Before and beyond ABA: upstream sensing and internal signals that determine ABA accumulation and response under abiotic stress
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (2): 375–379.
Published: 01 April 2005
... 54 Ishitani M. Xiong L-.M. Stevenson B. Zhu J.-K. Plant Cell 1997 9 1935 1949 abiotic stress abscisic acid (ABA) osmoregulation reactive oxygen species (ROS) upstream sensing upstream signalling Mammalian integrins are known to be involved in sensing...
Articles
Selective elimination of mitochondria from living cells induced by inhibitors of bioenergetic functions
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2004) 32 (6): 1070–1071.
Published: 26 October 2004
... Society 2004 elimination of mitochondria fission fusion mitochondrial inhibitors reactive oxygen species (ROS) When HeLa cells were treated for 48–72 h with uncouplers in combination with antimycine or myxothiazole, a significant (50–70%) fraction of the cells died but the rest...
Articles
Redox regulation of phosphatase function
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2004) 32 (6): 1018–1020.
Published: 26 October 2004
... 2004 hydrogen peroxide phosphatase protein tyrosine phosphatase (PTP) reactive oxygen species (ROS) redox signalling superoxide Regulated reversible phosphorylation of proteins and other cellular molecules plays a ubiquitous role in the control of cellular behaviour. Several different...
Articles
Reactive oxygen species in oncogenic transformation
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2003) 31 (6): 1441–1444.
Published: 01 December 2003
... of the Biochemical Society held at the University of Essex, Colchester, 2–4 July 2003 9 July 2003 © 2003 Biochemical Society 2003 apoptosis growth factor Mn superoxide dismutase Ras reactive oxygen species (ROS) senescence Abbreviations used: AP-1, activator protein-1; DPI...
